Highly diastereoselective preparation of (E)-alkenylsilanes bearing an α-chiral center

被引：34
作者：
Perrone, Sylvie [1 ]
Knochel, Paul [1 ]
机构：
[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 06期
关键词：
D O I：
10.1021/ol063097o
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The copper(I)-mediated anti-S(N)2' allylic substitution allows a highly stereoselective preparation of alkenylsilanes bearing a chiral center in the alpha-position with high transfer of chirality. These alkenylsilanes were converted into alpha,beta-unsaturated ketones or into the corresponding boronic esters without loss of the chiral information.
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页码：1041 / 1044
页数：4
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