Influenza Virus and SARS-CoV-2 Vaccines

被引:13
作者
Sandor, Adam M. [1 ,2 ,3 ,4 ]
Sturdivant, Michael S. [1 ,5 ]
Ting, Jenny P. Y. [1 ,2 ,3 ]
机构
[1] Univ North Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
[2] Univ North Carolina, Dept Genet, Chapel Hill, NC 27599 USA
[3] Univ North Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27599 USA
[4] Univ North Carolina, Div Pharmacoengn & Mol Pharmaceut, Eshelman Sch Pharm, Chapel Hill, NC 27599 USA
[5] Univ North Carolina, Biol & Biomed Sci Program, Chapel Hill, NC 27599 USA
关键词
NEUTRALIZING MONOCLONAL-ANTIBODIES; GUILLAIN-BARRE-SYNDROME; SEASONAL INFLUENZA; H1N1; INFLUENZA; DENDRITIC CELLS; PANDEMIC PREPAREDNESS; DEPENDENT ENHANCEMENT; AFFINITY MATURATION; ADAPTIVE IMMUNITY; B-CELLS;
D O I
10.4049/jimmunol.2001287
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Seasonal influenza and the current COVID-19 pandemic represent looming global health challenges. Efficacious and safe vaccines remain the frontline tools for mitigating both influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced diseases. This review will discuss the existing strategies for influenza vaccines and how these strategies have informed SARS-CoV-2 vaccines. It will also discuss new vaccine platforms and potential challenges for both viruses.
引用
收藏
页码:2509 / 2520
页数:12
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