Current Role of Chemotherapy in Nonmetastatic Nasopharyngeal Cancer

被引:28
作者
Bhattacharyya, Tapesh [1 ]
Babu, Geethu [2 ]
Kainickal, Cessal Thommachan [2 ]
机构
[1] Tata Med Ctr, Div Radiat Oncol, Kolkata, India
[2] Reg Canc Ctr, Div Radiat Oncol, Trivandrum, Kerala, India
关键词
BARR-VIRUS DNA; PLUS ADJUVANT CHEMOTHERAPY; RANDOMIZED PHASE-II; CONCURRENT CHEMORADIOTHERAPY; THERAPEUTIC GAIN; CARCINOMA; RADIOTHERAPY; TRIAL; MULTICENTER; FRACTIONATION;
D O I
10.1155/2018/3725837
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Nasopharyngeal carcinoma is highly radio-and chemosensitive tumor with its unique clinical and biological behavior. Treatment of stage I disease is radical radiotherapy alone. For stage II disease treatment is radiotherapy with or without chemotherapy. The standard of care for locally advanced nasopharyngeal cancer (stages III-IVB) is concurrent chemoradiation. Optimum timing and sequence of chemotherapy are not yet well-defined. The role of adjuvant and induction chemotherapy is debatable. Here we are going to highlight the role of chemotherapy in nasopharyngeal carcinoma, its benefit, and controversies regarding timing and sequences.
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页数:7
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