Clinical Guidelines for the Use of Antipruritic Drugs in the Control of the Most Frequent Pruritic Skin Diseases in Dogs

被引:11
作者
Bruet, Vincent [1 ]
Mosca, Marion [2 ]
Briand, Amaury [3 ]
Bourdeau, Patrick [4 ]
Pin, Didier [2 ]
Cochet-Faivre, Noelle [3 ,5 ]
Cadiergues, Marie-Christine [6 ,7 ]
机构
[1] Vet Dermatol Referral Serv, F-44100 Nantes, France
[2] Univ Lyon, VetAgro Sup, Interact Cells Environm, UPSP 2016 A104, F-69280 Marcy Letoile, France
[3] Ecole Natl Vet Alfort, Dept Dermatol, F-94700 Maisons Alfort, France
[4] ENVN Oniris Univ Nantes, Dept Clin Sci, F-44307 Nantes, France
[5] Lab Sante Anim, UMR BIPAR, F-94700 Maisons Alfort, France
[6] Univ Toulouse, Dept Clin Sci, ENVT, F-31076 Toulouse, France
[7] Univ Toulouse, INFINITy, INSERM, CNRS,UPS, F-31059 Toulouse, France
关键词
dog; pruritus; allergy; atopic dermatitis; glucocorticoids; antihistamines; ciclosporin; oclacitinib; lokivetmab; CANINE ATOPIC-DERMATITIS; CLIENT-OWNED DOGS; HYDROCORTISONE ACEPONATE SPRAY; ALLERGEN-SPECIFIC IMMUNOTHERAPY; TRIAMCINOLONE TOPICAL SOLUTION; IL-31; MONOCLONAL-ANTIBODY; PLACEBO-CONTROLLED TRIAL; URINARY-TRACT-INFECTION; CYCLOSPORINE-A THERAPY; LONG-TERM;
D O I
10.3390/vetsci9040149
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Pruritus is a common clinical sign in many skin disorders and is currently the main complaint in canine dermatology. Pruritic skin diseases can affect the quality of life of dogs and their owners. Several families of antipruritic drugs are available to help control pruritus in dogs. The aim of this review is to help practitioners select the most appropriate symptomatic treatment in the most frequent situations of dermatological pruritus in dogs. The molecules reviewed here are systemic and topical glucocorticoids, antihistamines, ciclosporin, oclacitinib and lokivetmab. A level of evidence (1, 2 or 3) has been established according to a detailed algorithm for each individual study in the literature published between 1990 and March 2021. The guidelines result from evidence grading using the strength of recommendation taxonomy (SoRT) and clinical recommendations using a thorough methodology.
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页数:32
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