DNA microarrays in clinical cancer research

被引：32

作者：

Wadlow, R

Ramaswamy, S

机构：

[1] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02129 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

来源：

CURRENT MOLECULAR MEDICINE | 2005年 / 5卷 / 01期

关键词：

D O I：

10.2174/1566524053152834

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The recent sequencing of the human genome, coupled with advances in biotechnology, is enabling the comprehensive molecular "profiling" of human tissues. In particular, DNA microarrays are powerful tools for obtaining global views of human tumor gene expression. Complex information from tumor "expression profiling" studies can, in turn, be used to create novel molecular cancer diagnostics. We discuss the utility of DNA microarray-based tumor profiling in clinical cancer research, highlight some important recent studies, and identify future avenues of research in this evolving field.

引用

页码：111 / 120

页数：10

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