Nuclear lipid signalling

被引:296
作者
Irvine, RF [1 ]
机构
[1] Univ Cambridge, Dept Pharmacol, Cambridge CB2 1QJ, England
关键词
D O I
10.1038/nrm1100
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
During the past twenty years, evidence has accumulated for the presence of phospholipids within the nuclei of eukaryotic cells. These phospholipids are distinct from those that are obviously present in the nuclear envelope. The best characterized of the intranuclear lipids are the inositol lipids that form the components of a phosphoinositide-phospholipase C cycle. However, exactly as has been discovered in the cytoplasm, this is just part of a complex picture that involves many other lipids and functions.
引用
收藏
页码:349 / 360
页数:12
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