LC-MS-SPE-NMR for the Isolation and Characterization of neo-Clerodane Diterpenoids from Teucrium luteum subsp flavovirens

被引：22

作者：

Castro, Amaya ^{[1
]}

Moco, Sofia ^{[2
]}

Coll, Josep ^{[1
]}

Vervoort, Jacques ^{[2
,3
]}

机构：

[1] CSIC, Inst Quim Avancada Catalunya, Barcelona, Spain

[2] Wageningen Univ, Biochem Lab, Wageningen, Netherlands

[3] Univ Wageningen, Wageningen NMR Ctr, Wageningen, Netherlands

来源：

JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 05期

关键词：

CYTOTOXIC CLERODANE DITERPENOIDS; STRUCTURAL ELUCIDATION; ANTIFEEDANT ACTIVITY; AJUGA; STEREOCHEMISTRY; SCUTELLARIA;

D O I：

10.1021/np9005025

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

neo-Clerodane diterpenes of plant origin are molecules difficult to monitor due to their nonspecific UV/vis absorption. The present work describes for the first time the application of the LC-MS-SPE-NMR technique for the isolation and characterization of three new neo-clerodane diterpenes, 3 beta-hydroxyteucroxylepin and teuluteumin A and teuluteumin B, from Teucrium luteum subsp. flavovirens, harvested from two different locations.

引用

页码：962 / 965

页数：4

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