Stabilized azomethine ylides derived from indeno[1,2-b] quinoxalinones in [3+2] cycloaddition reactions with electrophilic alkenes

被引：16

作者：

Korotaev, Vladislav Yu. ^{[1
]}

Zimnitskiy, Nikolay S. ^{[1
]}

Barkov, Alexey Yu. ^{[1
]}

Kutyashev, Igor B. ^{[1
]}

Sosnovskikh, Vyacheslav Ya. ^{[1
]}

机构：

[1] Ural Fed Univ, Inst Nat Sci & Math, 51 Lenina Ave, Ekaterinburg 620000, Russia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2018年 / 54卷 / 10期

基金：

俄罗斯基础研究基金会;

关键词：

6H-indeno[1,2-b] pyrido[3,2-e] pyrazin-6-one; 11H-indeno[1,2-b] quinoxalin-11-one; electrophilic alkenes; stabilized azomethine ylides; biological activity; 1,3-dipolar cycloaddition; multicomponent reactions; STEREOSELECTIVE 1,3-DIPOLAR CYCLOADDITION; POT 4-COMPONENT PROCEDURE; 4 COMPONENT SYNTHESIS; DIASTEREOSELECTIVE SYNTHESIS; 3,3,3-TRIHALOGENO-1-NITROPROPENES SYNTHESIS; PYRROLIDINE HETEROCYCLES; REGIOSELECTIVE SYNTHESIS; SPIRO PYRROLIZIDINES; FACILE SYNTHESIS; MULTICOMPONENT;

D O I：

10.1007/s10593-018-2369-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We provide a general and systematic review of all currently published data on the use of stabilized azomethine ylides derived from 11H-indeno[1,2-b] quinoxalin-11-one and 6H-indeno[1,2-b] pyrido[3,2-e] pyrazin-6-one in the synthesis of spiropyrrolidines and spiropyrrolizidines. The reaction conditions, as well as the regio- and stereoselectivity of the [3+2] cycloaddition process are discussed. Data on the biological activity of the obtained products are presented. There are 62 literature references.

引用

页码：905 / 922

页数：18

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