Overcoming limitations of current Antibody-Drug Conjugates (ADCs) by a novel linker technology

被引：1
|
作者：
Spycher, Philipp Rene [1 ]
Frei, Julia Carina [2 ]
Wehrmueller, Jori Elias [2 ]
Attinger-Toller, Isabella [1 ]
Grabulovski, Dragan [1 ]
Hechler, Torsten [3 ]
Kulke, Michael [3 ]
Pahl, Andreas [3 ]
Behe, Martin [2 ]
Schibli, Roger [2 ]
机构：
[1] ETH Honggerberg, Araris Biotech AG, Zurich, Switzerland
[2] Paul Scherrer Inst, Villigen, Switzerland
[3] Heidelberg Pharma Res GmbH, Ladenburg, Germany
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-LB-106
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-106
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Antibody-Drug Conjugates (ADCs)
    Laird, Trevor
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2014, 18 (09) : 1073 - 1073
  • [2] Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs)
    Reid, Emily E.
    Archer, Katie E.
    Shizuka, Manami
    Wilhelm, Alan
    Yoder, Nicholas C.
    Bai, Chen
    Fishkin, Nathan E.
    Harris, Luke
    Maloney, Erin K.
    Salomon, Paulin
    Hong, Erica
    Wu, Rui
    Ab, Olga
    Jin, Shan
    Lai, Katharine C.
    Sikka, Surina
    Chari, Ravi V. J.
    Miller, Michael L.
    ACS MEDICINAL CHEMISTRY LETTERS, 2019, 10 (08): : 1193 - 1197
  • [3] Antibody-Drug Conjugates (ADCs) - Biotherapeutic bullets
    Kitson, Sean L.
    Quinn, Derek J.
    Moody, Thomas S.
    Speed, David
    Watters, William
    Rozzell, David
    CHIMICA OGGI-CHEMISTRY TODAY, 2013, 31 (04) : 29 - 35
  • [4] Methods to Design and Synthesize Antibody-Drug Conjugates (ADCs)
    Yao, Houzong
    Jiang, Feng
    Lu, Aiping
    Zhang, Ge
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (02)
  • [5] Click-cleavable antibody-drug conjugates (ADCs)
    Rossin, Raffaella
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [6] Potential of antibody-drug conjugates (ADCs) for cancer therapy
    Marei, Hany E.
    Cenciarelli, Carlo
    Hasan, Anwarul
    CANCER CELL INTERNATIONAL, 2022, 22 (01)
  • [7] Antibody-drug conjugates (ADCs) in lung cancer treatment
    Wass, Romana E.
    Lang, David
    Horner, Andreas
    Lamprecht, Bernd
    MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY, 2024, 17 (03) : 198 - 203
  • [8] Antibody-drug conjugates (ADCs) - New targeted therapies
    Papakonstantinou G.
    memo - Magazine of European Medical Oncology, 2013, 6 (4) : 223 - 224
  • [9] Novel Chemical Linkers for Next-generation Antibody-drug Conjugates (ADCs)
    Tsuchikama, Kyoji
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2019, 139 (02): : 209 - 219
  • [10] Current progress and remaining challenges of peptide–drug conjugates (PDCs): next generation of antibody-drug conjugates (ADCs)?
    Dongyuan Wang
    Feng Yin
    Zigang Li
    Yu Zhang
    Chen Shi
    Journal of Nanobiotechnology, 23 (1)
12345