The impact of meningococcal conjugate vaccine (MenACWY-TT) on meningococcal carriage in Hajj Pilgrims returning to Turkey

被引：8

作者：

Tezer, Hasan ^{[1
]}

Gulhan, Belgin ^{[2
]}

Simge Gisi, Ayse ^{[2
]}

Nar Otgun, Selin ^{[3
,4
]}

Kanik-Yuksek, Saliha ^{[2
]}

Ozkaya-Parlakay, Aslinur ^{[2
]}

Kilic, Selcuk ^{[2
,5
]}

Unal Sahin, Nuriye ^{[6
]}

Simsek, Asiye Cigdem ^{[6
]}

Kara, Ates ^{[7
]}

机构：

[1] Gazi Univ, Fac Med, Pediat Infect Dis Dept, Ankara, Turkey

[2] Univ Hlth Sci, Dept Pediat Infect Dis, Ankara Child Hlth & Dis Hematol Oncol Training &, Ankara, Turkey

[3] Gen Directorate Publ Hlth, Microbiol Reference Labs, Ankara, Turkey

[4] Gen Directorate Publ Hlth, Biol Prod Directorate, Ankara, Turkey

[5] Minist Hlth, Gen Directorate Publ Hlth, Dept Microbiol Reference Lab, Ankara, Turkey

[6] Univ Hlth Sci, Publ Hlth Inst Turkey, Ankara, Turkey

[7] Hacettepe Univ, Fac Med, Pediat Infect Dept, Ihsan Dogramaci Childrens Hosp, Ankara, Turkey

来源：

HUMAN VACCINES & IMMUNOTHERAPEUTICS | 2020年 / 16卷 / 06期

关键词：

Meningococcal vaccine; Hajj pilgrim; conjugated meningococal vaccine; meningococal carriage; Turkey; NEISSERIA-MENINGITIDIS; PREVALENCE; DISEASE;

D O I：

10.1080/21645515.2019.1680084

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Meningococcal conjugate vaccine was administered for the first time to pilgrims in 2018 in Turkey prior to their departure to the Hajj. This study aimed to determine the effect of vaccination on the prevalence of Neisseria meningitidis carriage among the pilgrims returning to Turkey. This prospective paired (departing and arriving) cohort study included pilgrims aged 10-80 years and compared N.meningitidis carriage before and after pilgrimage. Oropharyngeal samples were collected from 229 pilgrims before departing for Mecca, Kingdom of Saudi Arabia (KSA) and after their return to Turkey. Meningococcal carriage was detected in 3.9% (n = 9) at the time of departure; all positive samples were serogroup B. Upon returning to Turkey,1 (0.4%) pilgrim, who was not a carrier before pilgrimage, was positive for serogroup B. This study is the first to examine meningococcal carriage following the administration of conjugate vaccine to Hajj pilgrims from Turkey.

引用

页码：1268 / 1271

页数：4

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