Euphatexols C - G, five new triterpenoids from the latex of Euphorbia resinifera

被引:5
作者
Li, Miao-Miao [1 ]
Qi, Yan-Ru [1 ]
Feng, Ya-Ping [1 ,2 ]
Liu, Wei [2 ]
Yuan, Tao [1 ]
机构
[1] Jiangxi Normal Univ, Coll Life Sci, Lab Effect Subst Jiangxi Genuine Med Mat, Nanchang 330022, Jiangxi, Peoples R China
[2] Yili Normal Univ, Key Lab Nat Prod Chem & Applicat Univ, Educ Dept Xinjiang Uygur Autonomous Reg, Yining 835000, Peoples R China
基金
中国国家自然科学基金;
关键词
Euphorbiaceae; triterpenoids; latex; Euphorbia resinifera; anti-inflammatory;
D O I
10.1080/10286020.2021.1935894
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Five new triterpenoids named as euphatexols C - G (1-5) were isolated from the latex of Euphorbia resinifera. Their chemical structures were determined by extensive spectroscopic analysis, including IR, HRMS, 1 D and 2 D NMR data. Compounds 1-5 showed moderate anti-inflammatory activity with IC50 values of 22.30, 48.04, 21.89, 38.15 and 41.15 mu M, respectively.
引用
收藏
页码:311 / 320
页数:10
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