The path to find an HIV vaccine

被引：6

作者：

Gray, Glenda E. ^{[1
]}

Corey, Lawrence ^{[2
]}

机构：

[1] South African Med Res Council, Cape Town, South Africa

[2] Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Div, 1124 Columbia St, Seattle, WA 98104 USA

来源：

JOURNAL OF THE INTERNATIONAL AIDS SOCIETY | 2021年 / 24卷 / 05期

关键词：

HIV vaccine; clinical trials; broadly neutralizing antibodies; NEUTRALIZING ANTIBODIES; EFFICACY; ALVAC;

D O I：

10.1002/jia2.25749

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页数：3

共 16 条

[1] Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine [J].

Baden, Lindsey R. ;

El Sahly, Hana M. ;

Essink, Brandon ;

Kotloff, Karen ;

Frey, Sharon ;

Novak, Rick ;

Diemert, David ;

Spector, Stephen A. ;

Rouphael, Nadine ;

Creech, C. Buddy ;

McGettigan, John ;

Khetan, Shishir ;

Segall, Nathan ;

Solis, Joel ;

Brosz, Adam ;

Fierro, Carlos ;

Schwartz, Howard ;

Neuzil, Kathleen ;

Corey, Larry ;

Gilbert, Peter ;

Janes, Holly ;

Follmann, Dean ;

Marovich, Mary ;

Mascola, John ;

Polakowski, Laura ;

Ledgerwood, Julie ;

Graham, Barney S. ;

Bennett, Hamilton ;

Pajon, Rolando ;

Knightly, Conor ;

Leav, Brett ;

Deng, Weiping ;

Zhou, Honghong ;

Han, Shu ;

Ivarsson, Melanie ;

Miller, Jacqueline ;

Zaks, Tal .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (05) :403-416

[2]

Barouch DH, 2018, LANCET, V392, P232, DOI [10.1016/S0140-6736(18)31364-3, 10.1016/s0140-6736(18)31364-3]

[3] Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition [J].

Corey, L. ;

Gilbert, P. B. ;

Juraska, M. ;

Montefiori, D. C. ;

Morris, L. ;

Karuna, S. T. ;

Edupuganti, S. ;

Mgodi, N. M. ;

deCamp, A. C. ;

Rudnicki, E. ;

Huang, Y. ;

Gonzales, P. ;

Cabello, R. ;

Orrell, C. ;

Lama, J. R. ;

Laher, F. ;

Lazarus, E. M. ;

Sanchez, J. ;

Frank, I. ;

Hinojosa, J. ;

Sobieszczyk, M. E. ;

Marshall, K. E. ;

Mukwekwerere, P. G. ;

Makhema, J. ;

Baden, L. R. ;

Mullins, J. I. ;

Williamson, C. ;

Hural, J. ;

McElrath, M. J. ;

Bentley, C. ;

Takuva, S. ;

Lorenzo, M. M. Gomez ;

Burns, D. N. ;

Espy, N. ;

Randhawa, A. K. ;

Kochar, N. ;

Piwowar-Manning, E. ;

Donnell, D. J. ;

Sista, N. ;

Andrew, P. ;

Kublin, J. G. ;

Gray, G. ;

Ledgerwood, J. E. ;

Mascola, J. R. ;

Cohen, M. S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (11) :1003-1014

[4] Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies [J].

Gao, Feng ;

Bonsignori, Mattia ;

Liao, Hua-Xin ;

Kumar, Amit ;

Xia, Shi-Mao ;

Lu, Xiaozhi ;

Cai, Fangping ;

Hwang, Kwan-Ki ;

Song, Hongshuo ;

Zhou, Tongqing ;

Lynch, Rebecca M. ;

Alam, S. Munir ;

Moody, M. Anthony ;

Ferrari, Guido ;

Berrong, Mark ;

Kelsoe, Garnett ;

Shaw, George M. ;

Hahn, Beatrice H. ;

Montefiori, David C. ;

Kamanga, Gift ;

Cohen, Myron S. ;

Hraber, Peter ;

Kwong, Peter D. ;

Korber, Bette T. ;

Mascola, John R. ;

Kepler, Thomas B. ;

Haynes, Barton F. .

CELL, 2014, 158 (03) :481-491

[5] Vaccine Efficacy of ALVAC-HIV and Bivalent Subtype C gp120-MF59 in Adults [J].

Gray, Glenda E. ;

Bekker, Linda-Gail ;

Laher, Fatima ;

Malahleha, Mookho ;

Allen, Mary ;

Moodie, Zoe ;

Grunenberg, Nicole ;

Huang, Yunda ;

Grove, Doug ;

Prigmore, Brittany ;

Kee, Jia J. ;

Benkeser, David ;

Hural, John ;

Innes, Craig ;

Lazarus, Erica ;

Meintjes, Graeme ;

Naicker, Nivashnee ;

Kalonji, Dishiki ;

Nchabeleng, Maphoshane ;

Sebe, Modulakgotla ;

Singh, Nishanta ;

Kotze, Philip ;

Kassim, Sheetal ;

Dubula, Thozama ;

Naicker, Vimla ;

Brumskine, William ;

Ncayiya, Cleon N. ;

Ward, Amy M. ;

Garrett, Nigel ;

Kistnasami, Girisha ;

Gaffoor, Zakir ;

Selepe, Pearl ;

Makhoba, Philisiwe B. ;

Mathebula, Matsontso P. ;

Mda, Pamela ;

Adonis, Tania ;

Mapetla, Katlego S. ;

Modibedi, Bontle ;

Philip, Tricia ;

Kobane, Gladys ;

Bentley, Carter ;

Ramirez, Shelly ;

Takuva, Simbarashe ;

Jones, Megan ;

Sikhosana, Mpho ;

Atujuna, Millicent ;

Andrasik, Michele ;

Hejazi, Nima S. ;

Puren, Adrian ;

Wiesner, Lubbe .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (12) :1089-1100

[6] Multiple roles for HIV broadly neutralizing antibodies [J].

Haynes, Barton F. ;

Burton, Dennis R. ;

Mascola, John R. .

SCIENCE TRANSLATIONAL MEDICINE, 2019, 11 (516)

[7] B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study [J].

Haynes, Barton F. ;

Kelsoe, Garnett ;

Harrison, Stephen C. ;

Kepler, Thomas B. .

NATURE BIOTECHNOLOGY, 2012, 30 (05) :423-433

[8] Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial [J].

Haynes, Barton F. ;

Gilbert, Peter B. ;

McElrath, M. Juliana ;

Zolla-Pazner, Susan ;

Tomaras, Georgia D. ;

Alam, S. Munir ;

Evans, David T. ;

Montefiori, David C. ;

Karnasuta, Chitraporn ;

Sutthent, Ruengpueng ;

Liao, Hua-Xin ;

DeVico, Anthony L. ;

Lewis, George K. ;

Williams, Constance ;

Pinter, Abraham ;

Fong, Youyi ;

Janes, Holly ;

DeCamp, Allan ;

Huang, Yunda ;

Rao, Mangala ;

Billings, Erik ;

Karasavvas, Nicos ;

Robb, Merlin L. ;

Ngauy, Viseth ;

de Souza, Mark S. ;

Paris, Robert ;

Ferrari, Guido ;

Bailer, Robert T. ;

Soderberg, Kelly A. ;

Andrews, Charla ;

Berman, Phillip W. ;

Frahm, Nicole ;

De Rosa, Stephen C. ;

Alpert, Michael D. ;

Yates, Nicole L. ;

Shen, Xiaoying ;

Koup, Richard A. ;

Pitisuttithum, Punnee ;

Kaewkungwal, Jaranit ;

Nitayaphan, Sorachai ;

Rerks-Ngarm, Supachai ;

Michael, Nelson L. ;

Kim, Jerome H. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (14) :1275-1286

[9] HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogene [J].

Jardine, Joseph G. ;

Kulp, Daniel W. ;

Havenar-Daughton, Colin ;

Sarkar, Anita ;

Briney, Bryan ;

Sok, Devin ;

Sesterhenn, Fabian ;

Ereno-Orbea, June ;

Kalyuzhniy, Oleksandr ;

Deresa, Isaiah ;

Hu, Xiaozhen ;

Spencer, Skye ;

Jones, Meaghan ;

Georgeson, Erik ;

Adachi, Yumiko ;

Kubitz, Michael ;

deCamp, Allan C. ;

Julien, Jean-Philippe ;

Wilson, Ian A. ;

Burton, Dennis R. ;

Crotty, Shane ;

Schief, William R. .

SCIENCE, 2016, 351 (6280) :1458-1463

[10]

MBIE, 2020, ANT FACT SHEET

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