Propofol-induced acute pancreatitis

被引：8

作者：

Csomor, J. ^{[1
,2
]}

Murinova, I. ^{[3
,4
]}

Broulikova, K. ^{[1
,2
]}

Kucerka, O. ^{[1
,2
]}

Sedlon, P. ^{[1
,2
]}

Jarosek, J. ^{[5
,6
]}

Urbanek, P. ^{[1
,2
]}

Zavoral, M. ^{[1
,2
]}

机构：

[1] Charles Univ Prague, Dept Internal Med, Med Fac 1, Prague, Czech Republic

[2] Cent Mil Hosp Prague, Prague, Czech Republic

[3] Mil Univ Hosp Prague, Dept Clin Pharm, Prague, Czech Republic

[4] Univ Vet & Pharmaceut Sci, Dept Appl Pharm, Brno, Czech Republic

[5] Charles Univ Prague, Fac Med 2, Surg Clin, Prague, Czech Republic

[6] Mil Univ Hosp Prague, Prague, Czech Republic

来源：

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2017年 / 42卷 / 04期

关键词：

adverse drug reaction; drug-induced acute pancreatitis; propofol; HYPERTRIGLYCERIDEMIA;

D O I：

10.1111/jcpt.12524

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

What is known and objectiveDrug-induced acute pancreatitis comprises only 0.5%-2% of all cases of acute pancreatitis. Propofol is a potentially dangerous drug that can cause acute pancreatitis, but this complication is extremely rare. Case summaryA 57-year-old patient developed acute pancreatitis after a planned thyroidectomy. As the common causes of acute pancreatitis were excluded, we believe that the pancreatitis was drug-induced, in this case by a single dose of propofol administered to the patient during the surgery. What is new and conclusionWe present a rare case of propofol-induced acute necrotising pancreatitis, which is to the best of our knowledge the first fatal case reported in an adult patient.

引用

页码：495 / 498

页数：4

共 11 条

[1] Drug-induced acute pancreatitis: An evidence-based review [J].

Badalov, Nison ;

Baradarian, Robin ;

Iswara, Kadirawel ;

Li, Jianjun ;

Steinberg, William ;

Tenner, Scott .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2007, 5 (06) :648-661

[2] Propofol-related infusion syndrome in intensive care patients [J].

Corbett, Stephanie Mallow ;

Montoya, Isaac D. ;

Moore, Frederick A. .

PHARMACOTHERAPY, 2008, 28 (02) :250-258

[3] Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: An analysis of frequency and risk factors [J].

Devlin, JW ;

Lau, AK ;

Tanios, MA .

PHARMACOTHERAPY, 2005, 25 (10) :1348-1352

[4] Acute pancreatitis after single-dose exposure to propofol - A case report and review of literature [J].

Jawaid, Q ;

Presti, ME ;

Neuschwander-Tetri, BA ;

Burton, FR .

DIGESTIVE DISEASES AND SCIENCES, 2002, 47 (03) :614-618

[5]

Jones MR, 2015, OCHSNER J, V15, P45

[6] Propofol-induced pancreatitis - Recurrence of pancreatitis after rechallenge [J].

Kumar, AN ;

Schwartz, DE ;

Lim, KG .

CHEST, 1999, 115 (04) :1198-1199

[7]

Muniraj T, 2012, J PANCREAS, V13, P451, DOI 10.6092/1590-8577/822

[8] A METHOD FOR ESTIMATING THE PROBABILITY OF ADVERSE DRUG-REACTIONS [J].

NARANJO, CA ;

BUSTO, U ;

SELLERS, EM ;

SANDOR, P ;

RUIZ, I ;

ROBERTS, EA ;

JANECEK, E ;

DOMECQ, C ;

GREENBLATT, DJ .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 30 (02) :239-245

[9] Drug-induced pancreatitis - An update [J].

Trivedi, CD ;

Pitchumoni, CS .

JOURNAL OF CLINICAL GASTROENTEROLOGY, 2005, 39 (08) :709-716

[10]

Urbanek K, 2012, ACUTE PANCREATITIS, P17

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