A holistic approach to healthy ageing: how can people live longer, healthier lives?

被引:29
作者
Calder, P. C. [1 ,2 ,3 ]
Carding, S. R. [4 ,5 ]
Christopher, G. [6 ]
Kuh, D. [7 ]
Langley-Evans, S. C. [8 ]
McNulty, H. [9 ]
机构
[1] Univ Southampton, Fac Med, Southampton, Hants, England
[2] Univ Hosp Southampton NHS Fdn Trust, NIHR Southampton Biomed Res Ctr, Southampton, Hants, England
[3] Univ Southampton, Southampton, Hants, England
[4] Univ East Anglia, Quadram Inst Biosci, Norwich, Norfolk, England
[5] Univ East Anglia, Norwich Med Sch, Norwich, Norfolk, England
[6] Univ West England, Fac Hlth & Appl Sci, Bristol, Avon, England
[7] UCL, Med Res Council Unit Lifelong Hlth & Ageing, London, England
[8] Univ Nottingham, Sch Bioscie, Loughborough LE12 5RD, Loughborough, England
[9] Ulster Univ, Sch Biomed Sci, Nutr Innovat Ctr Food & Hlth, Coleraine, Londonderry, North Ireland
基金
英国生物技术与生命科学研究理事会;
关键词
ageing; cognition; genetics; microbiome; nutrition; FOLIC-ACID SUPPLEMENTATION; VITAMIN-D; COGNITIVE DECLINE; HABIT FORMATION; OLDER-ADULTS; MEDITERRANEAN DIET; B VITAMINS; BONE MASS; HOMOCYSTEINE; METAANALYSIS;
D O I
10.1111/jhn.12566
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
BackgroundAlthough lifespan is increasing, there is no evidence to suggest that older people are experiencing better health in their later years than previous generations. Nutrition, at all stages of life, plays an important role in determining health and wellbeing. MethodsA roundtable meeting of UK experts on nutrition and ageing considered key aspects of the diet-ageing relationship and developed a consensus position on the main priorities for research and public health actions that are required to help people live healthier lives as they age. ResultsThe group consensus highlighted the requirement for a life course approach, recognising the multifactorial nature of the impact of ageing. Environmental and lifestyle influences at any life stage are modified by genetic factors and early development. The response to the environment at each stage of life can determine the impact of lifestyle later on. There are no key factors that act in isolation to determine patterns of ageing and it is a combination of environmental and social factors that drives healthy or unhealthy ageing. Too little is known about how contemporary dietary patterns and sedentary lifestyles will impact upon healthy ageing in future generations and this is a priority for future research. ConclusionsThere is good evidence to support change to lifestyle (i.e. diet, nutrition and physical) activity in relation to maintaining or improving body composition, cognitive health and emotional intelligence, immune function and vascular health. Lifestyle change at any stage of life may extend healthy lifespan, although the impact of early changes appears to be greatest.
引用
收藏
页码:439 / 450
页数:12
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