Monitoring Criminal Activity through Invisible Fluorescent "Peptide Coding" Taggants

被引：23

作者：

Gooch, James ^{[1
]}

Goh, Hilary ^{[2
]}

Daniel, Barbara ^{[1
]}

Abbate, Vincenzo ^{[3
]}

Frascione, Nunzianda ^{[1
]}

机构：

[1] Kings Coll London, Analyt & Environm Sci Div, 150 Stamford St, London SE1 9NH, England

[2] Natl Univ Singapore, Dept Biol Sci, 14 Sci Dr 4, Singapore 117543, Singapore

[3] Kings Coll London, Inst Pharmaceut Sci, 150 Stamford St, London SE1 9NH, England

来源：

ANALYTICAL CHEMISTRY | 2016年 / 88卷 / 08期

关键词：

BARCODES; CURRENCY; TAGS;

D O I：

10.1021/acs.analchem.6b00263

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Complementing the demand for effective crime reduction measures are the increasing availability of commercial forensic "taggants", which may be used to physically mark an object in order to make it uniquely identifiable. This study explores the use of a novel "peptide coding" reagents to establish evidence of contact transfer during criminal activity. The reagent, containing a fluorophore dispersed within an oil-based medium, also includes a unique synthetic peptide sequence that acts as a traceable "code" to identify the origin of the taggant. The reagent is detectable through its fluorescent properties, which then allows the peptide to be recovered by swabbing and extracted for electrospray ionization-mass spectrometry (ESI-MS) analysis via a simple liquid liquid extraction procedure. The performance of the reagent in variable conditions that mimic the limits of a real world use are investigated.

引用

页码：4456 / 4460

页数：5

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