Preparation of siloxane-containing vaterite/poly (L-lactic acid) hybrid microbeads with silicate and calcium ions-releasing ability

被引：0
作者：
Nakamura, Jin [1 ]
Poologasundarampillai, Gowsihan [1 ]
Obata, Akiko [1 ]
Kasuga, Toshihiro [1 ]
机构：
[1] Nagoya Inst Technol, Dept Frontier Mat, Grad Sch Engn, Showa Ku, Nagoya, Aichi 4668555, Japan
来源：
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN | 2010年 / 118卷 / 1378期
基金：
日本学术振兴会;
关键词：
Poly (L-lactic acid); Vaterite; Siloxane; Beads; Electrospray; Ion-releasing ability; SOFT-TISSUE AUGMENTATION; BIOACTIVE GLASS SCAFFOLD; CONE-JET MODE; ELECTROHYDRODYNAMIC ATOMIZATION; MINERALIZATION; REGENERATION; BIOPLASTIQUE; OSTEOBLASTS; EXPRESSION; MEMBRANES;
D O I：
10.2109/jcersj2.118.541
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Siloxane-containing vaterite (SiV)/poly (L-lactic acid) (PLLA) hybrids have the releasing-ability of silicate and calcium ions for gene-activation. In the present paper a new types of beads were prepared using the hybrids via an electrospraying method. The diameters of the beads were controlled in the range of similar to 65 to similar to 180 mu m by increasing the feeding rate from 0.1 to 0.9 ml/min. Depressed areas could be observed on the surface of the beads. The SiV particles with concentration of 10 and 20 wt % in the beads were completely enclosed by the PLLA matrix. These beads showed the controlled release of silicate and calcium ions in Tris buffer solution. (C) 2010 The Ceramic Society of Japan. All rights reserved.
引用
收藏
页码：541 / 544
页数：4
相关论文
共 21 条
[1]   The modulation of tissue-specific gene expression in rat nasal chondrocyte cultures by bioactive glasses [J].
Asselin, A ;
Hattar, S ;
Oboeuf, M ;
Greenspan, D ;
Berdal, A ;
Sautier, JM .
BIOMATERIALS, 2004, 25 (25) :5621-5630
[2]   TREATMENT OF DEEP CARTILAGE DEFECTS IN THE KNEE WITH AUTOLOGOUS CHONDROCYTE TRANSPLANTATION [J].
BRITTBERG, M ;
LINDAHL, A ;
NILSSON, A ;
OHLSSON, C ;
ISAKSSON, O ;
PETERSON, L .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (14) :889-895
[3]   CHIN AUGMENTATION USING MINIMALLY INVASIVE TECHNIQUE AND BIOPLASTIQUE [J].
ERSEK, RA ;
STOVALL, RB ;
VAZQUEZSALISBURY, A .
PLASTIC AND RECONSTRUCTIVE SURGERY, 1995, 95 (06) :985-992
[4]   BIOPLASTIQUE - A NEW TEXTURED COPOLYMER MICROPARTICLE PROMISES PERMANENCE IN SOFT-TISSUE AUGMENTATION [J].
ERSEK, RA ;
BEISANG, AA .
PLASTIC AND RECONSTRUCTIVE SURGERY, 1991, 87 (04) :693-702
[5]   Nodule formation and mineralisation of human primary osteoblasts cultured on a porous bioactive glass scaffold [J].
Gough, JE ;
Jones, JR ;
Hench, LL .
BIOMATERIALS, 2004, 25 (11) :2039-2046
[6]   Electrohydrodynamic atomization in the cone-jet mode physical modeling of the liquid cone and jet [J].
Hartman, RPA ;
Brunner, DJ ;
Camelot, DMA ;
Marijnissen, JCM ;
Scarlett, B .
JOURNAL OF AEROSOL SCIENCE, 1999, 30 (07) :823-849
[7]   Third-generation biomedical materials [J].
Hench, LL ;
Polak, JM .
SCIENCE, 2002, 295 (5557) :1014-+
[8]   Extracellular matrix formation and mineralization on a phosphate-free porous bioactive glass scaffold using primary human osteoblast (HOB) cells [J].
Jones, Julian R. ;
Tsigkou, Olga ;
Coates, Emily E. ;
Stevens, Molly M. ;
Polak, Julia M. ;
Hench, Larry L. .
BIOMATERIALS, 2007, 28 (09) :1653-1663
[9]   Human histology and persistence of various injectable filler substances for soft tissue augmentation [J].
Lemperle, G ;
Morhenn, V ;
Charrier, U .
AESTHETIC PLASTIC SURGERY, 2003, 27 (05) :354-366
[10]   Preparation of poly(L-lactic acid)-polysiloxane-calcium carbonate hybrid membranes for guided bone regeneration [J].
Maeda, H ;
Kasuga, T ;
Hench, LL .
BIOMATERIALS, 2006, 27 (08) :1216-1222
123