A near-infrared fluorescent probe for accurately diagnosing cancer by sequential detection of cysteine and H+

被引:24
作者
She, Zun-Pan [1 ]
Wang, Wen-Xin [1 ]
Mao, Guo-Jiang [2 ]
Jiang, Wen-Li [1 ]
Wang, Zhi-Qing [1 ]
Li, Yongfei [1 ,3 ]
Li, Chun-Yan [1 ]
机构
[1] Xiangtan Univ, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environm Friendly Chem & Applicat, Minist Educ,Coll Chem, Xiangtan 411105, Peoples R China
[2] Henan Normal Univ, Collaborat Innovat Ctr Henan Prov Green Mfg Fine, Henan Key Lab Organ Funct Mol & Drug Innovat, Minist Educ,Sch Chem & Chem Engn,Key Lab Green Ch, Xinxiang 453007, Henan, Peoples R China
[3] Xiangtan Univ, Coll Chem Engn, Xiangtan 411105, Peoples R China
基金
中国国家自然科学基金;
关键词
REAL-TIME DETECTION; SENSOR; VISUALIZATION; MITOCHONDRIA; APOPTOSIS; SHIFT; PH;
D O I
10.1039/d1cc01228b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A near-infrared fluorescent probe, CyAc, is synthesized for accurately diagnosing cancer in vivo by sequential detection of Cys and H+. CyAc can not only achieve a good distinction between normal cells and cancer cells, but also distinguish normal mice from tumor mice.
引用
收藏
页码:4811 / 4814
页数:4
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