Flow reactor approach for the facile and continuous synthesis of efficient Pd@Pt core-shell nanoparticles for acceptorless dehydrogenative synthesis of pyrimidines from alcohols and amidines

被引：9

作者：

Poly, Sharmin Sultana ^{[1
]}

Hashiguchi, Yuta ^{[2
]}

Sultana, Asima ^{[1
]}

Nakamura, Isao ^{[1
]}

Shimizu, Ken-ichi ^{[3
]}

Yasumura, Shunsaku ^{[3
]}

Fujitani, Tadahiro ^{[1
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol Tsukuba, Interdisciplinary Res Ctr Catalyt Chem, Tsukuba, Ibaraki 3058565, Japan

[2] Res Assoc High Throughput Design & Dev Adv Funct, Tsukuba, Ibaraki 3058565, Japan

[3] Hokkaido Univ, Inst Catalysis, N-21,W-10, Sapporo, Hokkaido 0010021, Japan

来源：

APPLIED CATALYSIS A-GENERAL | 2021年 / 619卷

关键词：

Acceptorless dehydrogenative coupling; Multicomponent reaction; Pyrimidines; Flow reactor; Core-shell catalyst; STRUCTURAL-CHARACTERIZATION; O-AMINOBENZAMIDES; CATALYSTS; QUINOLINES; OXIDATION; REDUCTION; METAL; ALLOY; DERIVATIVES; FABRICATION;

D O I：

10.1016/j.apcata.2021.118158

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Carbon supported Pd@Pt core-shell nanoparticles catalyst was prepared in a flow reactor toachieve enhanced catalytic activities with low Pt loading for the acceptorless dehydrogenative synthesis of pyrimidines. Spectroscopic (XAS analysis) and microscopic (HAADF-STEM) techniques reveled that the core-shell structure was formed by the applied preparation method. The Pd@Pt/PVP (polyvinylpyrrolidone)/C catalyst showed the activity for the three component one pot synthesis of pyrimidines through a series of consecutive reactions including oxidation of alcohols, C?C, and C?N coupling, followed by heterocyclization and dehydrogenation employing various primary alcohols, secondary alcohols, and amidines. The reaction mechanism on Pd@Pt/ PVP/C catalyst was explored by comparison with the control experiments.

引用

页数：8

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