In Vitro Activity of Ceftazidime-Avibactam against Contemporary Pseudomonas aeruginosa Isolates from US Medical Centers by Census Region, 2014

被引：32

作者：

Huband, Michael D. ^{[1
]}

Castanheira, Mariana ^{[1
]}

Flamm, Robert K. ^{[1
]}

Farrell, David J. ^{[1
]}

Jones, Ronald N. ^{[1
]}

Sader, Helio S. ^{[1
]}

机构：

[1] JMI Labs, North Liberty, IA USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2016年 / 60卷 / 04期

关键词：

BETA-LACTAMASE; RESISTANCE; STATES;

D O I：

10.1128/AAC.03056-15

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro antibacterial activities of ceftazidime-avibactam and comparator agents were evaluated using reference broth microdilution methods against 1,743 Pseudomonas aeruginosa isolates collected in 2014 from 69 U.S. medical centers, representing each of the nine census regions. Ceftazidime-avibactam demonstrated potent activity against P. aeruginosa, including many isolates not susceptible to ceftazidime, meropenem, and piperacillin-tazobactam. In each of the nine census regions, ceftazidime-avibactam demonstrated the highest percentage of susceptible isolates.

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收藏

页码：2537 / 2541

页数：5

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