Sukkula retrotransposon movements in the human genome

被引:5
作者
Cakmak, Buket [1 ]
Marakli, Sevgi [1 ]
Gozukirmizi, Nermin [1 ]
机构
[1] Istanbul Univ, Dept Mol Biol & Genet, Fac Sci, Istanbul, Turkey
关键词
Mobile genetic elements; human genome; IRAP; polymorphism; TRANSPOSABLE ELEMENTS; WHEAT CULTIVARS; MARKERS; BARLEY; REMAP; RICE; IRAP;
D O I
10.1080/13102818.2017.1316684
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Retrotransposons, a subclass of mobile genetic elements, have been discovered in many organisms. In this study, we identified a plant-specific retrotransposon (Sukkula) in the human genome (24 different DNA samples) by using retrotransposon-based molecular marker technique: inter-retrotransposon amplified polymorphism. There were five different groups related to the ages of the subjects. The polymorphism ratios were 8%-100% among all samples, 10%-91% among females (12 subjects) and 13%-100% among males (12 subjects). Moreover, we also observed 8%-91% polymorphism ratios when comparing males to females. To the best of our knowledge, this is one of the first reports on plant-specific retrotransposons in the human genome. The obtained findings are expected to contribute to broadening the knowledge about plant retrotransposons in the human genome and their role in human genome evolution.
引用
收藏
页码:756 / 760
页数:5
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