Subcutaneous Panniculitis-Like T-Cell Lymphoma with Hemophagocytic Syndrome in a Child

被引:12
作者
Gupta, Vishal [1 ]
Arava, Sudheer [2 ]
Bakhshi, Sameer [3 ]
Vashisht, Kanya Rani [1 ]
Reddy, Rakesh [3 ]
Gupta, Somesh [1 ]
机构
[1] All India Inst Med Sci, Dept Dermatol & Venereol, New Delhi 110029, India
[2] All India Inst Med Sci, Dept Pathol, New Delhi 110029, India
[3] All India Inst Med Sci, Dept Med Oncol, New Delhi 110029, India
关键词
CYTOPHAGIC HISTIOCYTIC PANNICULITIS; CYCLOSPORINE; CLASSIFICATION; FEATURES;
D O I
10.1111/pde.12776
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) characterized by subcutaneous infiltration of pleomorphic T-cells of the alpha/beta phenotype rarely affects children. Development of hemophagocytic syndrome (HPS) leads to a poor prognosis with this otherwise indolent lymphoma. We report a case of SPTCL in a 5-year-old child complicated by HPS treated successfully with combination chemotherapy. We discuss the potential pitfalls in reaching an early diagnosis and challenges in its management. Previously reported cases of SPTCL with HPS in children are briefly reviewed.
引用
收藏
页码:E72 / E76
页数:5
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