The Concept of Induced Membrane for Reconstruction of Long Bone Defects

被引：655

作者：

Masquelet, Alain C. ^{[1
]}

Begue, Thierry ^{[1
]}

机构：

[1] Med Univ Paris, Avicenne Hosp, Dept Orthoped & Traumatol, F-93009 Bobigny, Paris, France

来源：

ORTHOPEDIC CLINICS OF NORTH AMERICA | 2010年 / 41卷 / 01期

关键词：

Bone reconstruction; Bone defect; Membrane; Osteoinductive factors; Bone healing; OSTEOGENIC PROTEIN-1; POLYLACTIDE MEMBRANES; SEGMENTAL DEFECTS; SHEEP TIBIA; SURGERY;

D O I：

10.1016/j.ocl.2009.07.011

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Clinical, experimental, and fundamental studies have shown the interest of a foreign body-induced membrane to promote the consolidation of a conventional cancellous bone autograft for reconstruction of long bone defects. The main properties of the membrane are to prevent the resorption of the graft and to secrete growth factors. The induced membrane appears as a biological chamber, which allows the conception of numerous experimental models of bone reconstruction. This concept could probably be extended to other tissue repair.

引用

页码：27 / +

页数：12

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