Clinical outcomes after implantation of extended depth-of-focus AcrySof® Vivity® intraocular lens in eyes with low-grade epiretinal membrane

Purpose To evaluate the clinical outcomes of extended depth-of-focus (EDoF) AcrySof (R) Vivity (R) intraocular lens in eyes with low-grade epiretinal membrane (ERM). Methods Forty-five eyes with low-grade ERM and history of Vivity implantation were compared with 50 age-matched controls with Vivity implantation and no ERM. Eyes with ERM showing widening of the outer nuclear layer and loss of the foveal depression, but no ectopic inner foveal layer or outer retinal defect were eligible. Corrected and uncorrected distant visual acuity (CDVA and UDVA), uncorrected intermediate and near visual acuity (UIVA and UNVA), contrast sensitivity detected by area under the log contrast sensitivity function (AULCSF), Strehl ratio, area ratio, and occurrence of dysphotopsia were compared between groups. Results UDVA and CDVA were similar between groups (UDVA: 0.01 +/- 0.05 vs 0.03 +/- 0.06, P = 0.154; CDVA: 0.00 +/- 0.00 vs 0.00 +/- 0.02, P = 0.125). UIVA and mesopic AULCSF were significantly worse in eyes with ERM compared to those with no ERM (UIVA: 0.09 +/- 0.09 vs 0.14 +/- 0.10, P = 0.028; mesopic AULCSF: 1.26 +/- 0.15 vs 1.17 +/- 0.10, P = 0.013). The occurrence of dysphotopsia was similar in both groups (glare: P = 0.465; halo: P = 0.218; starburst: P = 0.457). Discussion Eyes with low-grade ERM showed comparable outcomes to eyes without ERM after Vivity IOL implantation. Implantation of this newly developed EDoF IOL with low addition can be of benefit to eyes with low-grade, reversible ERM that is limited to the inner retina.