Three new dioxopiperazine metabolites from a marine-derived fungus Aspergillus fumigatus Fres.

被引：34

作者：

Zhao, Wen Ying ^{[1
,2
]}

Zhu, Tian Jiao ^{[1
]}

Fan, Guo Tao ^{[1
]}

Liu, Hong Bing ^{[1
]}

Fang, Yu Chun ^{[1
]}

Gu, Qian Qun ^{[1
]}

Zhu, Wei Ming ^{[1
]}

机构：

[1] Ocean Univ China, Inst Marine Drugs & Food, Chinese Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China

[2] Qingdao Univ Sci & Technol, Qingdao 266042, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2010年 / 24卷 / 10期

关键词：

marine-derived fungus; Aspergillus fumigatus; dioxopiperazine metabolites; cytotoxicity; GLIOTOXIN;

D O I：

10.1080/14786410902726134

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Three new dioxopiperazine metabolites (1-3), together with two known compounds, N-acetyltyramine (4) and cyclo-(Ala-Val) (5), were isolated from a marine-derived fungus Aspergillus fumigatus Fres. Their structures were established by spectroscopic methods. Their cytotoxic activities against the K562 cell line were preliminarily evaluated by the sulphorhodamine B (SRB) method.

引用

收藏

页码：953 / 957

页数：5

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