Effects of drugs on the efficacy of radioiodine (131I) therapy in hyperthyroid patients

被引:10
作者
Oszukowska, Lidia [2 ]
Knapska-Kucharska, Malgorzata [2 ]
Lewinski, Andrzej [1 ,3 ]
机构
[1] Med Univ Lodz, Dept Endocrinol & Metab Dis, PL-93338 Lodz, Poland
[2] Med Univ Lodz, Dept Nucl Med & Oncol Endocrinol, PL-93338 Lodz, Poland
[3] Polish Mothers Mem Hosp Res Inst, Lodz, Poland
关键词
hyperthyroidism; medical treatment; (I-131) radioiodine therapy; GRAVES-DISEASE; RADIOACTIVE IODINE; THIONAMIDE WITHDRAWAL; ANTITHYROID DRUGS; CURE RATE; CARBIMAZOLE; PROPYLTHIOURACIL; GLUCOCORTICOIDS; OPHTHALMOPATHY; CONTROVERSIES;
D O I
10.5114/aoms.2010.13499
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The treatment of hyperthyroidism is targeted at reducing the production of thyroid hormones by inhibiting their synthesis or suppressing their release, as well as by controlling their influence on peripheral tissue (conservative therapy, medical treatment) Radical treatment includes surgical intervention to reduce the volume of thyroid tissue or damage of the mechanisms of thyroid hormone synthesis by radioiodine (I-131) administration Radioiodine (I-131) is a reactor radionuclide, produced as a result of uranium decomposition and emission of beta and gamma radiation The therapeutic effects of the isotope are obtained by the emission of p radiation In the paper, the effects of administered drugs (antithyroid, glucocorticosteroids, lithium carbonate, inorganic iodine, beta-blockers) on the final outcome of radioiodine therapy in patients with hyperthyroidism are discussed.
引用
收藏
页码:4 / 10
页数:7
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