Bleeding risk assessment for stroke patients on antithrombotic therapy

被引:3
作者
Castilla-Guerra, Luis [1 ]
del Carmen Fernandez-Moreno, Maria [2 ]
Manuel de la Vega-Sanchez, Juan [1 ]
Leon Jimenez, David [3 ]
机构
[1] Hosp Virgen Macarena, Unidad Riesgo Vasc, Unidad Gest Clin Med Interna, Seville, Spain
[2] Hosp Valme, Unidad Gest Clin Neurol, Seville, Spain
[3] Hosp Virgen Macarena, Unidad Gest Clin Cuidados Crit & Urgencias, Seville, Spain
来源
CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS | 2019年 / 31卷 / 06期
关键词
Antiaggregants; Anticoagulants; Stroke; Intracranial hemorrhage; Hemorrhagic risk; Antithrombotic treatment; TRANSIENT ISCHEMIC ATTACK; ATRIAL-FIBRILLATION; INTRACRANIAL HEMORRHAGE; ORAL ANTICOAGULANTS; METAANALYSIS; SCORE; WARFARIN; CLOPIDOGREL; PREVENTION; SCHEMES;
D O I
10.1016/j.arteri.2019.01.006
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Introduction: After an ischemic cerebrovascular event the risk of new ischemic events is high, therefore antithrombotic therapy are indicated to prevent stroke recurrence. Discussion: Despite its clear benefit, these therapies increase the risk of bleeding. Therefore, it is essential to identify high hemorrhagic risk patients. There are different predictive models of hemorrhage, in particular of intracranial hemorrhage, associated with the use of antiaggregants in patients who have presented an ischemic stroke or TIA, such as the CCSC, intracranial scales similar to B2LEED3S score or S2TOP-BLEED. However, though main international guidelines recommend the use of scales, in particular, the HAS-BLED score, to assess the risk of bleeding in anticoagulated patients, there is no specific recommendation in the case of the use of antiplatelet drugs. Conclusions: In this review we present the main models currently available for the prediction of bleeding of antithrombotic therapy in patients who have had a stroke or TIA. (C) 2019 Sociedad Espanola de Arteriosclerosis. Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:282 / 288
页数:7
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