C(sp3)-H bond functionalization by sequential hydride transfer/cyclization: electronic effect and steric effect controlled regioselectivity

被引：44
作者：
Wang, Liang [1 ]
Xiao, Jian [1 ]
机构：
[1] Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2016年 / 3卷 / 05期
基金：
中国国家自然科学基金;
关键词：
C-H FUNCTIONALIZATION; TERT-AMINOCYCLIZATION; ACID; SUBSTITUENT; ALKYLATION; ACTIVATION; AMINATION; SKELETON; CASCADE;
D O I：
10.1039/c6qo00043f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The electronic effect and steric effect have a dramatic impact on the fascinating cascade [1,n]-hydride transfer/cyclization. The regioselectivity of two potential hydrogen donors could be perfectly tuned to construct different skeletons.
引用
收藏
页码：635 / 638
页数：4
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