Tuning nanophase separation and drug delivery kinetics through spray drying and self-assembly

被引:11
|
作者
Fatnassi, Mohamed [1 ]
Tourne-Peteilh, Corine [1 ]
Cacciaguerra, Thomas [1 ]
Dieudonne, Philippe [2 ]
Devoisselle, Jean-Marie [1 ]
Alonso, Bruno [1 ]
机构
[1] CNRS ENSCM UM2 UM1, UMR 5253, ICGM MACS, F-34296 Montpellier 5, France
[2] Univ Montpellier 2, UMR 5587, CNRS, LCVN, F-34095 Montpellier 5, France
关键词
MESOPOROUS SILICA; SPHERES; MCM-41; IBUPROFEN; PROPERTY; RELEASE;
D O I
10.1039/b9nj00773c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new one-pot synthesis route associating sol-gel, self-assembly and spray drying allows the formation of microspheres with tuneable textures (worm-like mesophases, separated spheroid nanodomains, core-shell organisation) and drug delivery properties (from burst to delayed release).
引用
收藏
页码:607 / 610
页数:4
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