Adjuvant Alendronic Acid in the Management of Severe Cherubism: A Case Report and Literature Review

被引：2

作者：

Bradley, Daniel ^{[1
]}

Patel, Vinod ^{[2
]}

Honeyman, Calum ^{[3
]}

McGurk, Mark ^{[4
]}

机构：

[1] Univ Hosp Coventry & Warwickshire, Oral & Maxillofacial Surg Dept, Coventry, W Midlands, England

[2] Guys & St Thomas NHS Fdn Trust, Dept Oral Surg, Guys Dent Inst, London, England

[3] Canniesburn Plast Surg & Burns Unit, Plast Surg, Glasgow, Lanark, Scotland

[4] Univ Coll London Hosp, Oral & Maxillofacial Surg, Dept Head & Neck Surg, London, England

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2021年 / 79卷 / 03期

关键词：

GIANT-CELL TUMOR; FIBROUS DYSPLASIA; BISPHOSPHONATES; CHILDREN; THERAPY; PAMIDRONATE; CALCITONIN; DENOSUMAB; RECURRENT; TRIAL;

D O I：

10.1016/j.joms.2020.10.001

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Cherubism is a rare disease of the jaws characterized by bilateral symmetrical painless expansion of the mandible and maxilla. In extreme cases, larger lesions can become exophytic and have profound functional and esthetic implications. Several pharmacologic agents have been trialed in the treatment of cherubism with variable success reported. Bisphosphonates have not been significantly studied in this setting. We present a case where oral alendronic acid was used as an adjuvant treatment after surgical debulking of the maxilla in a 13-year-old boy with a severe case of cherubism. (C) 2020 Published by Elsevier Inc. on behalf of the American Association of Oral and Maxillofacial Surgeons

引用

页码：598 / 607

页数：10

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