Electrospun nanofibrous composite materials: a versatile platform for high efficiency protein adsorption and separation

被引：37
作者：
Fu, Qiuxia [1 ]
Duan, Cheng [1 ]
Yan, Zishuo [1 ]
Si, Yang [1 ]
Liu, Lifang [1 ]
Yu, Jianyong [2 ]
Ding, Bin [1 ,2 ]
机构：
[1] Donghua Univ, Coll Text, Minist Educ, Key Lab Text Sci & Technol, Shanghai 201620, Peoples R China
[2] Donghua Univ, Innovat Ctr Text Sci & Technol, Shanghai 200051, Peoples R China
来源：
COMPOSITES COMMUNICATIONS | 2018年 / 8卷
基金：
中国国家自然科学基金;
关键词：
Electrospun nanofibers; Protein adsorption; Surface functionalization; Chromatography; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; AFFINITY MEMBRANE; CELLULOSE NANOFIBER; BACTERIAL CELLULOSE; PURIFICATION; SURFACE; NANOPARTICLES; OPPORTUNITIES; FABRICATION; CAPACITY;
D O I：
10.1016/j.coco.2017.11.007
中图分类号：
TB33 [复合材料];
学科分类号：
摘要：
Highly effective separation and purification of protein are extremely important for the development of pharmaceutical industry, which still remains a great challenge. As a kind of frontier new material, electrospun nanofibers show vast perspectives in fabricating high performance protein adsorption materials attributing to their competitive structure advantages involving large specific surface area, high porosity, good pore channel connectivity, easy to surface functionalization, controllable single fiber and aggregate structure. Herein, we detailedly summarize the recent progress in the design concepts, synthesis and structure control of electrospun nanofibrous composite materials with different functional interfaces for the separation and purification of proteins. Furthermore, the current challenges and future development directions in this rapidly developed field are also highlighted in this review.
引用
收藏
页码：92 / 100
页数：9
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