Molecular pathology of Alzheimer's disease

被引：1
作者：
Yamazaki, T [1 ]
Ihara, Y [1 ]
机构：
[1] Univ Tokyo, Fac Med, Dept Neuropathol, Bunkyo Ku, Tokyo 113, Japan
来源：
NEUROPATHOLOGY | 1997年 / 17卷 / 04期
关键词：
Alzheimer's disease; amyloid beta-protein; apolipoprotein E; presenilins;
D O I：
10.1111/j.1440-1789.1997.tb00051.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Recent molecular and cellular approaches to the nature of Alzheimer's disease (AD) have revealed that the disease has a heterogenous genetic background. Thus, AD is not a disease but a syndrome, In the present article we review the significance of the causative and susceptibility genes of AD identified to date and discuss future perspectives of AD research.
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页码：263 / 269
页数：7
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