A Ten-year-long Update on Radiation Proctitis Among Prostate Cancer Patients Treated With Curative External Beam Radiotherapy

被引:32
作者
Ferini, Gianluca [1 ]
Pergolizzi, Stefano [2 ]
机构
[1] REM Radioterapia, Via Penninazzo 11, I-95029 Catania, Italy
[2] Univ Messina, Dept Biomed & Dent Sci Morphol & Funct Images, Messina, Italy
来源
IN VIVO | 2021年 / 35卷 / 03期
关键词
Radiation proctitis; External Beam Radiotherapy; prostate cancer; side effects; Intensity modulated radiotherapy; Image guided radiotherapy; dosimetry; supportive care; prevention; cancer care; review; ARGON PLASMA COAGULATION; HYPERBARIC-OXYGEN TREATMENT; DOSE-RATE BRACHYTHERAPY; RECTAL TOXICITY; ADVERSE EVENTS; THERAPY; TRIAL; MULTICENTER; CRITERIA; WALL;
D O I
10.21873/invivo.12390
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
This comprehensive synopsis summarizes the most relevant information obtained from a systematic analysis of studies of the last decade on radiation proctitis, one of the most feared radioinduced side effects among prostate cancer patients treated with curative external beam radiotherapy. The present review provides a useful support to radiation oncologists for limiting the onset or improving the treatment of radiation proctitis. This work shows that the past decade was a harbinger of significant new evidence in technological advances and technical tricks to avoid radiation proctitis, in addition to dosimetric perspectives and goals, understanding of pathogenesis, diagnostic work-up and treatment. We believe that a well-rounded knowledge of such an issue is fundamental for its appropriate management.
引用
收藏
页码:1379 / 1391
页数:13
相关论文
共 102 条
[1]   What is the impact of diabetes mellitus on radiation induced acute proctitis after radical radiotherapy for adenocarcinoma prostate? A prospective longitudinal study [J].
Alashkham, Abduelmenem ;
Paterson, Catherine ;
Hubbard, Stephen ;
Nabi, Ghulam .
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY, 2019, 14 :59-63
[2]   Can Angiotensin-Converting Enzyme Inhibitors Reduce the Incidence, Severity, and Duration of Radiation Proctitis? [J].
Alashkham, Abduelmenem ;
Paterson, Catherine ;
Rauchhaus, Petra ;
Nabi, Ghulam .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2016, 94 (01) :93-101
[3]   An observational trial to establish the effect of hyperbaric oxygen treatment on pelvic late radiation tissue injury due to radiotherapy [J].
Andren, James ;
Bennett, Michael H. .
DIVING AND HYPERBARIC MEDICINE, 2020, 50 (03) :250-255
[4]  
[Anonymous], 1995, Int J Radiat Oncol Biol Phys, V31, P1049
[5]   Acute toxicity and its dosimetric correlates for high-risk prostate cancer treated with moderately hypofractionated radiotherapy [J].
Arunsingh, Moses ;
Mallick, Indranil ;
Prasath, Sriram ;
Arun, B. ;
Sarkar, Sandip ;
Shrimali, Raj Kumar ;
Chatterjee, Sanjoy ;
Achari, Rimpa .
MEDICAL DOSIMETRY, 2017, 42 (01) :18-23
[6]   The Impact of Clinical Factors on the Development of Late Radiation Toxicity: Results from the Medical Research Council RT01 Trial (ISRCTN47772397) [J].
Barnett, G. C. ;
De Meerleer, G. ;
Gulliford, S. L. ;
Sydes, M. R. ;
Elliott, R. M. ;
Dearnaley, D. P. .
CLINICAL ONCOLOGY, 2011, 23 (09) :613-624
[7]   Chromosome Damage and Cell Proliferation Rates in In Vitro Irradiated Whole Blood as Markers of Late Radiation Toxicity After Radiation Therapy to the Prostate [J].
Beaton, Lindsay A. ;
Ferrarotto, Catherine ;
Marro, Leonora ;
Samiee, Sara ;
Malone, Shawn ;
Grimes, Scott ;
Malone, Kyle ;
Wilkins, Ruth C. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 85 (05) :1346-1352
[8]   OUTCOMES AFTER INTENSITY-MODULATED VERSUS CONFORMAL RADIOTHERAPY IN OLDER MEN WITH NONMETASTATIC PROSTATE CANCER [J].
Bekelman, Justin E. ;
Mitra, Nandita ;
Efstathiou, Jason ;
Liao, Kaijun ;
Sunderland, Robert ;
Yeboa, Deborah N. ;
Armstrong, Katrina .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2011, 81 (04) :E325-E334
[9]   Postoperative radiotherapy for prostate cancer: the sooner the better and potential to reduce toxicity even further [J].
Borghetti, Paolo ;
Spiazzi, Luigi ;
Cozzaglio, Claudia ;
Pedretti, Sara ;
Caraffini, Bruno ;
Triggiani, Luca ;
Greco, Diana ;
Bardoscia, Lilia ;
Barbera, Fernando ;
Buglione, Michela ;
Magrini, Stefano Maria .
RADIOLOGIA MEDICA, 2018, 123 (01) :63-70
[10]   Assessing correlations between the spatial distribution of the dose to the rectal wall and late rectal toxicity after prostate radiotherapy: an analysis of data from the MRC RT01 trial (ISRCTN 47772397) [J].
Buettner, Florian ;
Gulliford, Sarah L. ;
Webb, Steve ;
Sydes, Matthew R. ;
Dearnaley, David P. ;
Partridge, Mike .
PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (21) :6535-6548