Autoimmune hepatitis associated with Graves' disease

被引：17

作者：

Cui, BL

Abe, M

Hidata, S

Nakanishi, S

Matsuura, B

Michitaka, K

Yamamoto, K

Horiike, N

Onji, M ^{[1
]}

机构：

[1] Ehime Univ, Sch Med, Dept Internal Med 3, Shigenobu, Ehime 7910295, Japan

[2] Ehime Univ, Sch Med, Endoscopy Ctr, Matsuyama, Ehime 790, Japan

[3] Matsuyama Shimin Hosp, Dept Gastroenterol, Matsuyama, Ehime, Japan

来源：

INTERNAL MEDICINE | 2003年 / 42卷 / 04期

关键词：

autoimmune hepatitis; Graves' disease; propylthiouracil; steroid therapy; liver histology;

D O I：

10.2169/internalmedicine.42.331

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 31-year-old woman with Graves' disease with a 12-month-history of propylthiouracil intake and autoantibodies in the sera was admitted to our hospital. The differential diagnosis between autoimmune hepatitis and propylthiouracil-induced hepatitis was intractable. Steroid therapy was started and she showed a complete response to the treatment. Liver biopsy demonstrated acute hepatitis and plasma cell infiltration. A second liver biopsy, which was performed 10 months after starting steroid therapy, showed some inflammatory cells in the portal tracts. These findings suggest that she had been suffering from autoimmune hepatitis.

引用

页码：331 / 335

页数：5

共 19 条

[1] Clinical characteristics of autoimmune hepatitis with histological features of acute hepatitis [J].

Abe, M ;

Hiasa, Y ;

Masumoto, T ;

Kumagi, T ;

Akbar, SMF ;

Ninomiya, T ;

Matsui, H ;

Michitaka, K ;

Horiike, N ;

Onji, M .

HEPATOLOGY RESEARCH, 2001, 21 (03) :213-219

[2] International Autoimmune Hepatitis Group Report:: review of criteria for diagnosis of autoimmune hepatitis [J].

Alvarez, E ;

Berg, PA ;

Bianchi, FB ;

Bianchi, L ;

Burroughs, AK ;

Cancado, EL ;

Chapman, RW ;

Cooksley, WGE ;

Czaja, AJ ;

Desmet, VJ ;

Donaldson, RT ;

Eddleston, ALWF ;

Fainboim, L ;

Heathcote, J ;

Homberg, JC ;

Hoofnagle, JH ;

Kakumu, S ;

Krawitt, EL ;

Mackay, IR ;

MacSween, RNM ;

Maddrey, WC ;

Manns, MP ;

McFarlane, IG ;

zum Büschenfelde, KHM ;

Mieli-Vergani, G ;

Nakanuma, Y ;

Nishioka, M ;

Penner, E ;

Porta, G ;

Portmann, BC ;

Reed, WD ;

Rodes, J ;

Schalm, SW ;

Scheuer, PJ ;

Schrumpf, E ;

Seki, T ;

Toda, G ;

Tsuji, T ;

Tygstrup, N ;

Vergani, D ;

Zeniya, M .

JOURNAL OF HEPATOLOGY, 1999, 31 (05) :929-938

[3]

BISCOVENEAU M, 2000, ENDOCR PRACT, V6, P387

[4] Propylthiouracil-induced fulminant hepatitis: Case report and review of the literature [J].

Deidiker, R ;

deMello, DE .

PEDIATRIC PATHOLOGY & LABORATORY MEDICINE, 1996, 16 (05) :845-852

[5] Propylthiouracil-induced severe hepatitis: A case report and review of the literature [J].

Ichiki, Y ;

Akahoshi, M ;

Yamashita, N ;

Morita, C ;

Maruyama, T ;

Horiuchi, T ;

Hayashida, K ;

Ishibashi, H ;

Niho, Y .

JOURNAL OF GASTROENTEROLOGY, 1998, 33 (05) :747-750

[6] A case of Graves' disease associated with autoimmune hepatitis and mixed connective tissue disease [J].

Inoue, K ;

Okajima, T ;

Tanaka, E ;

Ando, B ;

Takeshita, M ;

Masuda, A ;

Yamamoto, M ;

Sakai, K .

ENDOCRINE JOURNAL, 1999, 46 (01) :173-177

[7]

Kim HJ, 2001, AM J GASTROENTEROL, V96, P165

[8] Medical progress - Autoimmune hepatitis [J].

Krawitt, EL .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (14) :897-903

[9] PROPYLTHIOURACIL HEPATOTOXICITY - A REVIEW AND CASE PRESENTATION [J].

LEVY, M .

CLINICAL PEDIATRICS, 1993, 32 (01) :25-29

[10] HEPATIC-INJURY DURING PROPYLTHIOURACIL THERAPY IN PATIENTS WITH HYPERTHYROIDISM - A COHORT STUDY [J].

LIAW, YF ;

HUANG, MJ ;

FAN, KD ;

LI, KL ;

WU, SS ;

CHEN, TJ .

ANNALS OF INTERNAL MEDICINE, 1993, 118 (06) :424-428

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