The bacterial universal stress protein:: function and regulation

被引：371

作者：

Kvint, K ^{[1
]}

Nachin, L ^{[1
]}

Diez, A ^{[1
]}

Nyström, T ^{[1
]}

机构：

[1] Univ Gothenburg, Dept Cell & Mol Biol, S-41390 Gothenburg, Sweden

来源：

CURRENT OPINION IN MICROBIOLOGY | 2003年 / 6卷 / 02期

关键词：

D O I：

10.1016/S1369-5274(03)00025-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The universal stress protein A (UspA) superfamily encompasses an ancient and conserved group of proteins that are found in bacteria, Archea, fungi, flies and plants. The Escherichia coli UspA is produced in response to a large number of different environmental onslaughts and UspA is one of the most abundant proteins in growth-arrested cells. Although insights into the regulation of the E coli uspA gene have been gained, the exact roles of the Usp proteins and Usp domains remain enigmatic; they appear, in some cases, to be linked to resistance to DNA-damaging agents and to respiratory uncouplers.

引用

页码：140 / 145

页数：6

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