New horizons in the extraction of bioactive compounds using deep eutectic solvents: A review

被引:416
作者
Zainal-Abidin, Mohamad Hamdi [1 ]
Hayyan, Maan [1 ,2 ]
Hayyan, Adeeb [1 ,2 ]
Jayakumar, Natesan Subramanian [1 ]
机构
[1] Univ Malaya, UMCiL, Dept Chem Engn, Kuala Lumpur 50603, Malaysia
[2] Univ Malaya, IHRUM, Acad Islamic Studies, Kuala Lumpur 50603, Malaysia
关键词
Ionic liquid; Green solvent; Anti-oxidant; Anti-cancer; Anti-inflammatory; Separation technology; MICROWAVE-ASSISTED EXTRACTION; AQUEOUS 2-PHASE SYSTEM; QUATERNARY AMMONIUM-SALTS; BIO-IONIC LIQUIDS; VIRGIN OLIVE OIL; CHOLINE CHLORIDE; PHENOLIC-COMPOUNDS; GREEN EXTRACTION; ANTIINFLAMMATORY ACTIVITY; EFFICIENT EXTRACTION;
D O I
10.1016/j.aca.2017.05.012
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
With the rapid development of ionic liquid analogues, termed 'deep eutectic solvents' (DESs), and their application in a wide range of chemical and biochemical processes in the past decade, the extraction of bioactive compounds has attracted significant interest. Recently, numerous studies have explored the extraction of bioactive compounds using DESs from diverse groups of natural sources, including animal and plant sources. This review summarizes the-state-of-the-art effort dedicated to the application of DESs in the extraction of bioactive compounds. The aim of this review also was to introduce conventional and recently-developed extraction techniques, with emphasis on the use of DESs as potential extractants for various bioactive compounds, such as phenolic acid, flavonoids, tanshinone, keratin, tocols, terpenoids, carrageenans, xanthones, isoflavones, a-mangostin, genistin, apigenin, and others. In the near future, DESs are expected to be used extensively for the extraction of bioactive compounds from various sources. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 23
页数:23
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