Identification and characterization of circadian clock genes in the pea aphid Acyrthosiphon pisum

被引：50

作者：

Cortes, T. ^{[1
]}

Ortiz-Rivas, B. ^{[1
]}

Martinez-Torres, D. ^{[1
]}

机构：

[1] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia 46071, Spain

来源：

INSECT MOLECULAR BIOLOGY | 2010年 / 19卷

关键词：

aphid; photoperiod; clock genes; circadian expression; PHOTOPERIODIC TIME MEASUREMENT; PITCHER-PLANT MOSQUITO; DROSOPHILA-MELANOGASTER; TRANSCRIPTION FACTORS; EXPRESSION PATTERNS; NATURAL-SELECTION; FEEDBACK LOOP; FLESH FLY; LONG-DAY; PERIOD;

D O I：

10.1111/j.1365-2583.2009.00931.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The molecular basis of circadian clocks is highly evolutionarily conserved and has been best characterized in Drosophila and mouse. Analysis of the Acyrthosiphon pisum genome revealed the presence of orthologs of the following genes constituting the core of the circadian clock in Drosophila: period (per), timeless (tim), Clock, cycle, vrille, and Pdp1. However, the presence in A. pisum of orthologs of a mammal-type in addition to a Drosophila-type cryptochrome places the putative aphid clockwork closer to the ancestral insect system than to the Drosophila one. Most notably, five of these putative aphid core clock genes are highly divergent and exhibit accelerated rates of change (especially per and tim orthologs) suggesting that the aphid circadian clock has evolved to adapt to (unknown) aphid-specific needs. Additionally, with the exception of jetlag (absent in the aphid) other genes included in the Drosophila circadian clock repertoire were found to be conserved in A. pisum. Expression analysis revealed circadian rhythmicity for some core genes as well as a significant effect of photoperiod in the amplitude of oscillations.

引用

页码：123 / 139

页数：17

共 78 条

[1] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].

Altschul, SF ;

Madden, TL ;

Schaffer, AA ;

Zhang, JH ;

Zhang, Z ;

Miller, W ;

Lipman, DJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402

[2] Regulation of copulation duration by period and timeless in Drosophila melanogaster [J].

Beaver, LM ;

Giebultowicz, JM .

CURRENT BIOLOGY, 2004, 14 (16) :1492-1497

[3] Noncircadian regulation and function of clock genes period and timeless in oogenesis of Drosophila melanogaster [J].

Beaver, LM ;

Rush, BL ;

Gvakharia, BO ;

Giebultowicz, JM .

JOURNAL OF BIOLOGICAL RHYTHMS, 2003, 18 (06) :463-472

[4] Loss of circadian clock function decreases reproductive fitness in males of Drosophila melanogaster [J].

Beaver, LM ;

Gvakharia, BO ;

Vollintine, TS ;

Hege, DM ;

Stanewsky, R ;

Giebultowicz, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (04) :2134-2139

[5] Circadian rhythms from multiple oscillators: Lessons from diverse organisms [J].

Bell-Pedersen, D ;

Cassone, VM ;

Earnest, DJ ;

Golden, SS ;

Hardin, PE ;

Thomas, TL ;

Zoran, MJ .

NATURE REVIEWS GENETICS, 2005, 6 (07) :544-556

[6]

Bradshaw WE, 2003, EVOLUTION, V57, P2342, DOI 10.1111/j.0014-3820.2003.tb00246.x

[7] Evolution -: Tantalizing timeless [J].

Bradshaw, William ;

Holzapfel, Christina .

SCIENCE, 2007, 316 (5833) :1851-1852

[8] Evolution of animal photoperiodism [J].

Bradshaw, William E. ;

Holzapfel, Christina M. .

ANNUAL REVIEW OF ECOLOGY EVOLUTION AND SYSTEMATICS, 2007, 38 :1-25

[9] Constructing a feedback loop with circadian clock molecules from the silkmoth, Antheraea pernyi [J].

Chang, DC ;

McWatters, HG ;

Williams, JA ;

Gotter, AL ;

Levine, JD ;

Reppert, SM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (40) :38149-38158

[10] A novel C-terminal domain of Drosophila PERIOD inhibits dCLOCK:CYCLE-mediated transcription [J].

Chang, DC ;

Reppert, SM .

CURRENT BIOLOGY, 2003, 13 (09) :758-762

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