Possible role of phospholipid nanotubes in directed transport of membrane vesicles

被引:32
作者
Iglic, A [1 ]
Hägerstrand, H
Bobrowska-Hägerstrand, M
Arrigler, V
Kraij-Iglic, V
机构
[1] Univ Ljubljana, Fac Elect Engn, Appl Phys Lab, SL-1000 Ljubljana, Slovenia
[2] Abo Akad Univ, Dept Biol, FIN-20520 Turku, Finland
[3] Univ Ljubljana, Fac Med, Inst Biophys, SL-1000 Ljubljana, Slovenia
关键词
phospholipid nanotubes; membrane vesicle; directed transport; deviatoric elasticity;
D O I
10.1016/S0375-9601(03)00449-3
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We indicate that membrane nanotubes may have an important role in directed transport of membrane vesicles between different membrane-enclosed compartments in cells. We present experimental evidence that small blebs of phospholipid nanotube may travel along the nanotube and act as vehicles for transporting the enclosed solution. We have also observed similar small membrane blebs of a long membrane tube in red blood cells. In both cases the small vesicles seem to be a distended integral part of the membrane tube and not independent vesicles entrapped within the tube. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:493 / 497
页数:5
相关论文
共 22 条
[1]  
ANGELOVA MI, 1992, PROG COLL POL SCI S, V89, P127
[2]   INSTABILITY AND PEARLING STATES PRODUCED IN TUBULAR MEMBRANES BY COMPETITION OF CURVATURE AND TENSION [J].
BARZIV, R ;
MOSES, E .
PHYSICAL REVIEW LETTERS, 1994, 73 (10) :1392-1395
[3]   BORON-NITRIDE NANOTUBES [J].
CHOPRA, NG ;
LUYKEN, RJ ;
CHERREY, K ;
CRESPI, VH ;
COHEN, ML ;
LOUIE, SG ;
ZETTL, A .
SCIENCE, 1995, 269 (5226) :966-967
[4]  
Cooper GM., 2000, The Development and Causes of Cancer, V2nd
[5]   ENTROPY-DRIVEN TENSION AND BENDING ELASTICITY IN CONDENSED-FLUID MEMBRANES [J].
EVANS, E ;
RAWICZ, W .
PHYSICAL REVIEW LETTERS, 1990, 64 (17) :2094-2097
[6]   Biomembrane templates for nanoscale conduits and networks [J].
Evans, E ;
Bowman, H ;
Leung, A ;
Needham, D ;
Tirrell, D .
SCIENCE, 1996, 273 (5277) :933-935
[7]  
FISCHER TM, 1992, J PHYS II, V2, P337, DOI 10.1051/jp2:1992137
[8]  
Goldstein RE, 1996, J PHYS II, V6, P767, DOI 10.1051/jp2:1996210
[9]   VESICULATION INDUCED BY AMPHIPHILES IN ERYTHROCYTES [J].
HAGERSTRAND, H ;
ISOMAA, B .
BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 982 (02) :179-186
[10]   Vectorial budding of vesicles by asymmetrical enzymatic formation of ceramide in giant liposomes [J].
Holopainen, JM ;
Angelova, MI ;
Kinnunen, PKJ .
BIOPHYSICAL JOURNAL, 2000, 78 (02) :830-838