Association between obesity and chronic renal disease

被引：3

作者：

Navarro, Gustavo ^{[2
]}

Ardiles, Leopoldo ^{[1
]}

机构：

[1] Univ Austral Chile, Lab Nefrol, Fac Med, Valdivia, Chile

[2] Univ Austral Chile, Alumno Programa Especializac Med Interna, Valdivia, Chile

来源：

REVISTA MEDICA DE CHILE | 2015年 / 143卷 / 01期

关键词：

Cardiovascular System; Obesity; Renal Insufficiency; CHRONIC KIDNEY-DISEASE; REACTIVE PROTEIN-LEVELS; BODY-MASS INDEX; ADIPOSE-TISSUE; INSULIN-RESISTANCE; ANGIOTENSIN-II; CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME; BARIATRIC SURGERY; WEIGHT-REDUCTION;

D O I：

10.4067/S0034-98872015000100010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A higher frequency of chronic renal disease is observed in obese patients, suggesting a pathogenic association between both conditions. Obesity unmasks clinical manifestations of chronic kidney disease such as high blood pressure, which may accelerate its progression. Obesity also promotes hyper filtration and the appearance of microalbuminuria, activates the renin-angiotensin-aldosterone system and is associated with high levels of pro-inflammatory cytokines. Therefore weight reduction may slow the progression of chronic renal disease and reduce its associated cardiovascular risk factors.

引用

页码：77 / 84

页数：8

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