Disagreement of diameter and volume measurements for pulmonary nodule size estimation in CT lung cancer screening

被引:62
作者
Heuvelmans, Marjolein A. [1 ]
Walter, Joan E. [1 ]
Vliegenthart, Rozemarijn [1 ]
van Ooijen, Peter M. A. [1 ]
De Bock, Geertruida H. [2 ]
de Koning, Harry J. [3 ]
Oudkerk, Matthijs [1 ]
机构
[1] Univ Groningen, Univ Med Ctr Groningen, Ctr Med Imaging North East Netherlands, Groningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands
[3] Erasmus MC, Dept Publ Hlth, Rotterdam, Netherlands
关键词
imaging/CT MRI etc; lung cancer;
D O I
10.1136/thoraxjnl-2017-210770
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
We studied 2240 indeterminate solid nodules (volume 50-500 mm(3)) to determine the correlation of diameter and semi-automated volume measurements for pulmonary nodule size estimation. Intra-nodular diameter variation, defined as maximum minus minimum diameter through the nodule's center, varied by 2.8 mm (median, IQR: 2.2-3.7 mm), so above the 1.5 mm cutoff for nodule growth used in Lung CT Screening Reporting and Data System (Lung-RADS). Using mean or maximum axial diameter to assess nodule volume led to a substantial mean overestimation of nodule volume of 47.2% and 85.1%, respectively, compared to semi-automated volume. Thus, size of indeterminate nodules is poorly represented by diameter.
引用
收藏
页码:779 / 781
页数:3
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