Analysis of the active components of silymarin

被引：230

作者：

Kvasnicka, F

Bíba, B

Sevcík, R

Voldrich, M

Krátká, J

机构：

[1] Inst Chem Technol, CR-16628 Prague 6, Czech Republic

[2] IVAX CR, Opava 74770 7, Czech Republic

来源：

JOURNAL OF CHROMATOGRAPHY A | 2003年 / 990卷 / 1-2期

关键词：

silymarin; pharmaceutical analysis; antioxidants; silychristin; silybin; isosilybin; silydianin;

D O I：

10.1016/S0021-9673(02)01971-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Silymarin is an antihepatotoxic substance isolated from fruits of Silybum marianum. Possibly due to their antioxidant and membrane stabilizing properties, the compounds have been shown to protect different organs and cells against a number of insults. The content and composition of main silymarin components (silybin, isosilybin, silydianin and silychristin) in various pharmaceuticals were analysed using HPLC and newly developed capillary zone electrophoresis method. Antioxidant properties expressed as total antioxidant status (TAS) of silymarin components were studied. Results of TAS were correlated with electropherograms and chromatograms. (C) 2002 Elsevier Science B.V. All rights reserved.

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页码：239 / 245

页数：7

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