Genomes, transcriptomes, and proteomes - Molecular medicine and its impact on medical practice

被引：14
作者：
Gerling, IC
Solomon, SS
Bryer-Ash, M
机构：
[1] Univ Tennessee, Hlth Sci Ctr, VAMC Res 151, Div Endocrinol,Dept Med, Memphis, TN 38104 USA
[2] Univ Tennessee, Hlth Sci Ctr, Dept Pharmacol, Memphis, TN 38104 USA
[3] Vet Affairs Med Ctr, Res Serv, Memphis, TN USA
[4] Vet Affairs Med Ctr, Med Serv, Memphis, TN USA
[5] Univ Calif Los Angeles, Gonda Diabet Ctr, Dept Med, Los Angeles, CA 90095 USA
[6] W Los Angeles Vet Adm Med Ctr, Los Angeles, CA USA
来源：
ARCHIVES OF INTERNAL MEDICINE | 2003年 / 163卷 / 02期
关键词：
D O I：
10.1001/archinte.163.2.190
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The human genome project and the technological breakthroughs it has produced have moved the field of molecular medicine forward with breathtaking speed. This will impact not only the advance of scientific discoveries and the way science is conducted but also the clinical practice of medicine. In this review we explain the basic principles of these new technologies. Their potential use and impact are demonstrated by using diabetes mellitus as an example of a common and serious medical disorder. Finally, several potentially adverse consequences of "excessive" knowledge are discussed.
引用
收藏
页码：190 / 198
页数：9
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