A combination of Deferoxamine mesylate and minimally invasive surgery with hematoma lysis for evacuation of intracerebral hemorrhage

被引：13

作者：

Pandey, Aditya S. ^{[1
]}

Daou, Badih J. ^{[1
]}

Chaudhary, Neeraj ^{[1
]}

Xi, Guohua ^{[1
]}

机构：

[1] Univ Michigan, Dept Neurol Surg, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 2020年 / 40卷 / 02期

关键词：

Deferoxamine; intracerebral hemorrhage; hematoma lysis; intracerebral hematoma evacuation;

D O I：

10.1177/0271678X19892660

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Intracerebral hemorrhage is associated with significant morbidity and mortality. Some clinical trials demonstrated a trend towards benefit with surgical evacuation of intracerebral hemorrhage, without strong statistically significant results. Subsequent studies focused on minimally invasive techniques. Improved outcomes were more likely with surgical reduction of intracerebral hemorrhage volume to <= 15 mL. Deferoxamine is currently being evaluated as a therapeutic tool in intracerebral hemorrhage with promising results. There continues to be a lack of level I evidence supporting medical and surgical tools for intracerebral hemorrhage evacuation. Could a combination of minimally invasive surgery with hematoma lysis and Deferoxamine result in more effective hematoma evacuation?

引用

页码：456 / 458

页数：3

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