Neurocircuitry of aggression and aggression seeking behavior: nose poking into brain circuitry controlling aggression

被引:58
作者
Aleyasin, Hossein
Flanigan, Meghan E.
Russo, Scott J. [1 ]
机构
[1] Icahn Sch Med Mt Sinai, Fishberg Dept Neurosci, New York, NY 10029 USA
关键词
CONDITIONED PLACE PREFERENCE; PREFRONTAL CORTEX; POSITIVE REINFORCEMENT; NUCLEUS-ACCUMBENS; LATERAL HABENULA; DOPAMINE SYSTEM; DELTA-FOSB; MICE; HYPOTHALAMUS; REWARD;
D O I
10.1016/j.conb.2018.02.013
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Aggression is an innate behavior that helps individuals succeed in environments with limited resources. Over the past few decades, neurobiologists have identified neural circuits that promote and modulate aggression; however, far less is known regarding the motivational processes that drive aggression. Recent research suggests that aggression can activate reward centers in the brain to promote positive valence. Here, we review major recent findings regarding neural circuits that regulate aggression, with an emphasis on those regions involved in the rewarding or reinforcing properties of aggressive behavior.
引用
收藏
页码:184 / 191
页数:8
相关论文
共 57 条
[1]   INTERMALE SOCIAL AGGRESSION - SUPPRESSION BY MEDIAL PREOPTIC AREA LESIONS [J].
ALBERT, DJ ;
WALSH, ML ;
GORZALKA, BB ;
MENDELSON, S ;
ZALYS, C .
PHYSIOLOGY & BEHAVIOR, 1986, 38 (02) :169-173
[2]   A diencephalic mechanism for the expression of rage with special reference to the sympathetic nervous system [J].
Bard, P .
AMERICAN JOURNAL OF PHYSIOLOGY, 1928, 84 (03) :490-515
[3]   High and abnormal forms of aggression in rats with extremes in trait anxiety - Involvement of the dopamine system in the nucleus accumbens [J].
Beiderbeck, Daniela I. ;
Reber, Stefan O. ;
Havasi, Andrea ;
Bredewold, Remco ;
Veenema, Alexa H. ;
Neumann, Inga D. .
PSYCHONEUROENDOCRINOLOGY, 2012, 37 (12) :1969-1980
[4]   Structural and functional alterations in the prefrontal cortex after post-weaning social isolation: relationship with species-typical and deviant aggression [J].
Biro, Laszlo ;
Toth, Mate ;
Sipos, Eszter ;
Bruzsik, Biborka ;
Tulogdi, Aron ;
Bendahan, Samuel ;
Sandi, Carmen ;
Haller, Jozsef .
BRAIN STRUCTURE & FUNCTION, 2017, 222 (04) :1861-1875
[5]   Problems in the study of rodent aggression [J].
Blanchard, RJ ;
Wall, PM ;
Blanchard, DC .
HORMONES AND BEHAVIOR, 2003, 44 (03) :161-170
[6]   Afferent and efferent projections of the anterior cortical amygdaloid nucleus in the mouse [J].
Cadiz-Moretti, Bernardita ;
Abellan-Alvaro, Maria ;
Pardo-Bellver, Cecilia ;
Martinez-Garcia, Fernando ;
Lanuza, Enrique .
JOURNAL OF COMPARATIVE NEUROLOGY, 2017, 525 (13) :2929-2954
[7]   The pleasure of revenge: retaliatory aggression arises from a neural imbalance toward reward [J].
Chester, David S. ;
DeWall, C. Nathan .
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 2016, 11 (07) :1173-1182
[8]   Corticolimbic Function in Impulsive Aggressive Behavior [J].
Coccaro, Emil F. ;
Sripada, Chandra Sekhar ;
Yanowitch, Rachel N. ;
Phan, K. Luan .
BIOLOGICAL PSYCHIATRY, 2011, 69 (12) :1153-1159
[9]   A Double-Blind, Randomized, Placebo-Controlled Trial of Fluoxetine in Patients With Intermittent Explosive Disorder [J].
Coccaro, Emil F. ;
Lee, Royce J. ;
Kavoussi, Richard J. .
JOURNAL OF CLINICAL PSYCHIATRY, 2009, 70 (05) :653-662
[10]   The rewarding effect of aggression is reduced by nucleus accumbens dopamine receptor antagonism in mice [J].
Couppis, Maria H. ;
Kennedy, Craig H. .
PSYCHOPHARMACOLOGY, 2008, 197 (03) :449-456