Preparation of frozen sections

BACKGROUND. For dermatologists the preparation of frozen sections means micrographic surgery. The preparation of frozen sections is meant to be rapid, but has multiple, discrete steps that demand attention to detail. OBJECTIVE. The objective was to summarize both the proven and the cutting-edge techniques of frozen section preparation. MATERIALS AND METHODS. Reports from the medical literature were used to augment techniques used in our practices. CONCLUSION. We dissect each step of micrographic cancer removal, report on the standard and preferred methods of tissue preparation, and summarize the progress achieved in the past decade.