Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds

被引:51
|
作者
Saide, Assunta [1 ]
Martinez, Kevin A. [1 ]
Ianora, Adrianna [1 ]
Lauritano, Chiara [1 ]
机构
[1] Staz Zool Anton Dohrn, Marine Biotechnol Dept, I-80121 Naples, Italy
关键词
microalgae; pharmaceuticals; bioactive molecules; marine biotechnology; DINOFLAGELLATE AMPHIDINIUM-CARTERAE; NITRIC-OXIDE INHIBITORS; MARINE DINOFLAGELLATE; ANTIOXIDANT ACTIVITY; BETA-CAROTENE; CHLORELLA-VULGARIS; OXIDATIVE STRESS; IN-VITRO; DUNALIELLA-SALINA; NATURAL-PRODUCTS;
D O I
10.3390/ijms22094383
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Microalgae are known to produce a plethora of compounds derived from the primary and secondary metabolism. Different studies have shown that these compounds may have allelopathic, antimicrobial, and antipredator activities. In addition, in vitro and in vivo screenings have shown that several compounds have interesting bioactivities (such as antioxidant, anti-inflammatory, anticancer, and antimicrobial) for the possible prevention and treatment of human pathologies. Additionally, the enzymatic pathways responsible for the synthesis of these compounds, and the targets and mechanisms of their action have also been investigated for a few species. However, further research is necessary for their full exploitation and possible pharmaceutical and other industrial applications. Here, we review the current knowledge on the chemical characteristics, biological activities, mechanism of action, and the enzymes involved in the synthesis of microalgal metabolites with potential benefits for human health.
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页数:40
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