Upholding a role for EMT in pancreatic cancer metastasis

被引：208

作者：

Aiello, Nicole M. ^{[1
,2
]}

Brabletz, Thomas ^{[3
]}

Kang, Yibin ^{[4
]}

Angela Nieto, M. ^{[5
]}

Weinberg, Robert A. ^{[6
,7
,8
]}

Stanger, Ben Z. ^{[1
,2
]}

机构：

[1] Univ Penn, Perelman Sch Med, Abramson Family Canc Res Inst, Dept Med, Philadelphia, PA 19104 USA

[2] Univ Penn, Perelman Sch Med, Abramson Family Canc Res Inst, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA

[3] FAU Univ Erlangen Nuernberg, Nikolaus Fiebiger Ctr Mol Med, Expt Med 1, D-91054 Erlangen, Germany

[4] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA

[5] Inst Neurociencias CSIC UMH, Avda Ramon y Cajal S-N, Alacant 03550, Spain

[6] Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA

[7] Ludwig MIT Ctr Mol Oncol, Cambridge, MA 02142 USA

[8] MIT, Dept Biol, 77 Massachusetts Ave, Cambridge, MA 02142 USA

来源：

NATURE | 2017年 / 547卷 / 7661期

关键词：

D O I：

10.1038/nature22963

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：E7 / E8

页数：2

共 3 条

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Angela Nieto, M. ;

Huang, Ruby Yun-Ju ;

Jackson, Rebecca A. ;

Thiery, Jean Paul .

CELL, 2016, 166 (01) :21-45

[2] EMT and Dissemination Precede Pancreatic Tumor Formation [J].

Rhim, Andrew D. ;

Mirek, Emily T. ;

Aiello, Nicole M. ;

Maitra, Anirban ;

Bailey, Jennifer M. ;

McAllister, Florencia ;

Reichert, Maximilian ;

Beatty, Gregory L. ;

Rustgi, Anil K. ;

Vonderheide, Robert H. ;

Leach, Steven D. ;

Stanger, Ben Z. .

CELL, 2012, 148 (1-2) :349-361

[3] Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer [J].

Zheng, Xiaofeng ;

Carstens, Julienne L. ;

Kim, Jiha ;

Scheible, Matthew ;

Kaye, Judith ;

Sugimoto, Hikaru ;

Wu, Chia-Chin ;

LeBleu, Valerie S. ;

Kalluri, Raghu .

NATURE, 2015, 527 (7579) :525-+

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