Fission yeast synaptobrevin is involved in cytokinesis and cell elongation

被引:40
|
作者
Edamatsu, M [1 ]
Toyoshima, YY [1 ]
机构
[1] Univ Tokyo, Grad Sch Arts & Sci, Meguro Ku, Tokyo 1538902, Japan
关键词
Schizosaccharomyces pombe; fission yeast; cytokinesis; membrane trafficking; SNARE; synaptobrevin;
D O I
10.1016/S0006-291X(03)00017-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Synaptobrevin is a vesicle-associated membrane protein playing an essential role in regulated vesicle transport. In this study, we characterized Syb1, synaptobrevin of Schizosaccharomyces pombe. Syb1 was located on various sizes of vesicle-like structures in the cytoplasm and enriched in the medial region and cell ends. Transport of Syb1 to the medial region was mainly dependent on F-actin and Myo52/Myo4. Syb1 is essential for cell viability and most of the syb1-null cells showed a round or short cylindrical form. These results suggest that Syb1 is involved in membrane trafficking of cytokinesis and cell elongation. (C) 2003 Elsevier Science (USA). All rights reserved.
引用
收藏
页码:641 / 645
页数:5
相关论文
共 50 条
  • [21] ACTION RING FORMATION AND CYTOKINESIS IN FISSION YEAST
    CHANG, F
    SAWIN, K
    WOLLARD, A
    NURSE, P
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, : 335 - 335
  • [22] The Roles of Septins in Regulating Fission Yeast Cytokinesis
    Zheng, Shengnan
    Zheng, Biyu
    Fu, Chuanhai
    JOURNAL OF FUNGI, 2024, 10 (02)
  • [23] A transglutaminase-like protein participates in cytokinesis and cell morphogenesis in fission yeast
    Pollard, L.
    Lord, M.
    MOLECULAR BIOLOGY OF THE CELL, 2011, 22
  • [24] Coordination of cell polarity and cytokinesis by fission yeast kinase Orb2.
    Magliozzi, J. O.
    Moseley, J. B.
    MOLECULAR BIOLOGY OF THE CELL, 2018, 29 (26) : 177 - 177
  • [25] Dividing the Spoils of Growth and the Cell Cycle: The Fission Yeast as a Model for the Study of Cytokinesis
    Goya, Anupama
    Takaine, Masak
    Simanis, Viesturs
    Nakano, Kentaro
    CYTOSKELETON, 2011, 68 (02) : 69 - 88
  • [26] Phosphatidylethanolamine Is Required for Normal Cell Morphology and Cytokinesis in the Fission Yeast Schizosaccharomyces pombe
    Luo, Jun
    Matsuo, Yasuhiro
    Gulis, Galina
    Hinz, Haylee
    Patton-Vogt, Jana
    Marcus, Stevan
    EUKARYOTIC CELL, 2009, 8 (05) : 790 - 799
  • [27] Elongation factors are involved in cytokinesis of sea urchin eggs
    Fujimoto, Hirotaka
    Mabuchi, Issei
    GENES TO CELLS, 2010, 15 (02) : 123 - 135
  • [28] Comparative analysis of cytokinesis in buddina yeast, fission yeast and animal cells
    Balasubramanian, MK
    Bi, EF
    Glotzer, M
    CURRENT BIOLOGY, 2004, 14 (18) : R806 - R818
  • [29] Cytokinesis in fission yeast: a story of rings, rafts and walls
    Rajagopalan, S
    Wachtler, V
    Balasubramanian, M
    TRENDS IN GENETICS, 2003, 19 (07) : 403 - 408
  • [30] Counting cytokinesis proteins globally and locally in fission yeast
    Wu, JQ
    Pollard, TD
    SCIENCE, 2005, 310 (5746) : 310 - 314