Atranones A-G, from the toxigenic mold Stachybotrys chartarum

被引:54
作者
Hinkley, SF [1 ]
Mazzola, EP [1 ]
Fettinger, JC [1 ]
Lam, YF [1 ]
Jarvis, BB [1 ]
机构
[1] Univ Maryland, Dept Chem & Biochem, JIFSAN, College Pk, MD 20742 USA
关键词
Stachybotrys chartarum (S. atra); diterpenoids; dolabellanes; enol lactones;
D O I
10.1016/S0031-9422(00)00231-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Atranones A-G have been isolated from the toxigenic fungus Stachybotrys chartarum. These compounds contain several unusual features including an enol-lactone as part of a 3,7-dioxabicyclo[3.3.0]octane-2-one ring system fused to an 11-membered ring. Two new dolabellane diterpenes, related in structure to the atranones were also isolated, which suggests a diterpenoid origin for the C-24 atranones. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:663 / 673
页数:11
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