Cytokines in the perinatal period - Part II

被引：9
作者：
Chau, A. [1 ,2 ,3 ]
Markley, J. C. [1 ,2 ,4 ]
Juang, J. [1 ,2 ]
Tsen, L. C. [1 ,2 ]
机构：
[1] Brigham & Womens Hosp, Div Obstet Anesthesia, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St,CWN L1, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Univ British Columbia, Dept Anesthesiol Pharmacol & Therapeut, Vancouver, BC V5Z 1M9, Canada
[4] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Anesthesia & Perioperat Care, San Francisco, CA USA
来源：
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA | 2016年 / 26卷
关键词：
AMNIOTIC-FLUID INTERLEUKIN-6; TUMOR-NECROSIS-FACTOR; GESTATIONAL DIABETES-MELLITUS; MAJOR SURGICAL STRESS; PRETERM LABOR; INFLAMMATORY RESPONSE; GENERAL-ANESTHESIA; TNF-ALPHA; ANTIINFLAMMATORY CYTOKINES; ALVEOLAR MACROPHAGES;
D O I：
10.1016/j.ijoa.2015.12.006
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
A contemporary, robust immunologic explanation for common obstetric conditions remains elusive; why some pregnant women are more susceptible to developing preeclampsia or preterm labor is not completely understood. We explore the immunology behind four important and commonly encountered pregnancy-related conditions: preeclampsia, recurrent miscarriage, preterm labor and gestational diabetes. For each condition, we summarize the current understanding of cytokines implicated in the pathogenesis, discuss the impact of anesthesia and analgesia on selected cytokine profiles, and suggest potential opportunities for clinical and research interventions. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：48 / 58
页数：11
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