A non-invasive, in-vivo, bubble sizing instrument

被引:0
作者
Magari, PJ [1 ]
Kline-Schoder, RJ [1 ]
Stoedefalke, BH [1 ]
Butler, BD [1 ]
机构
[1] Creare Res & Dev Inc, Hanover, NH 03755 USA
来源
1997 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1 & 2 | 1997年
关键词
D O I
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中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Creare has developed and demonstrated a non-invasive, in-vivo instrument for detecting, classifying, and sizing gaseous emboli which can result in decompression sickness. The instrument consists of a low-frequency pump transducer to excite the fundamental vibration mode of the bubbles and a high-frequency imaging transducer to observe the resonance. Because the bubbles act as nonlinear mixers, sidebands will be present in the high-frequency return signal at plus and minus the pump frequency, if and only if, there is a resonant bubble. The instrument was extensively tested in vitro over a wide range of bubble size distributions. Preliminary experiments were performed on an animal model to demonstrate the device in vivo.
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页码:1205 / 1210
页数:6
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